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Análise in silico de um novo composto possível inibidor de ciclooxigenase 2 utilizando docking molecular
(Universidade Federal de São Carlos, 2021-01-04)
This work describes the study of the formation of complexes between the enzyme cyclooxygenase (COX-2) and some of its inhibitors. For this purpose, the known inhibitors celecoxib (CEL), rofecoxib (RCX) and Korean 21 and ...
Clonagem e expressão de uma xilanase presente no (Meta)transcriptoma do Cupim da espécie Heterotermes tenuis e sua importante aplicação na produção de biocombustíveis
(Universidade Federal de São Carlos, 2021-01-08)
Xylanases are an important group of enzymes responsible for the hydrolysis of the xylan glycosidic chain forming xylose and xylobiosis. Mainly noteworthy is endo-1,4-β-xylanase, a hemicellulase capable of cleaving the β-1,4 ...
Reflexões sobre o papel dos valores nas aplicações biotecnológicas
(Universidade Federal de São Carlos, 2021-01-29)
Biotechnology is the central object of study, it will be classified here as an activity originated in the boundary between science (chemical and biological) and engineering, under the influence of several sets of values, ...
Aumento da produção de fenazina-1-ácido carboxílico em E. coli: efeito da superexpressão dos genes tktA e ppsA
(Universidade Federal de São Carlos, 2021-11-11)
Secondary metabolites known as phenazines are nitrogenated aromatic compounds produced particularly by the bacterium genera Pseudomonas and Streptomyces, with applications in fields like biological pest control and biosensors ...
Avaliação do co-cultivo de bactérias e microalga Chlorella sorokiniana no tratamento de efluentes
(Universidade Federal de São Carlos, 2021-09-03)
Pollution is a social and health problem, the lack of sewer treatment together with its incorrect disposal are one of the leading sources of aquatic pollution. Microalgae are microorganisms which have the potential for ...
Predição de proteínas parceiras de interação da trealase, enzima relacionada com a patogenicidade de Xanthomonas citri subsp. citri
(Universidade Federal de São Carlos, 2021-06-17)
Known as one of the main phytopathologies that affect the citrus industry worldwide, citrus canker is caused by the bacterium Xanthomonas citri subsp. citri (XAC) and is responsible for causing premature drop and reduction ...
Acinetobacter baumannii: por que novos antibióticos são necessários ?
(Universidade Federal de São Carlos, 2021-06-21)
Acinetobacter baumannii, an opportunistic gram-negative coccobacillus bacterium belonging to the genus Acinetobacter, has gained worldwide importance as a public health problem. This bacterium has an extraordinary ability ...
Potencial de fungos endofíticos no controle de doenças pós-colheita de frutas
(Universidade Federal de São Carlos, 2021-06-18)
Postharvest losses are significant to the agricultural production yield and generate a considerable amount of food losses every year in a world constantly affected by starvation and food unsafety. Moreover, sustainable ...
A autofagia é necessária para a segregação de DNA mitocondrial no Fígado
(Universidade Federal de São Carlos, 2021-06-24)
Mutations in the mitochondrial genome (mtDNA) are ubiquitous in humans and can lead to a broad spectrum of disorders. However, due to the presence of multiple mtDNA molecules in the cell, coexistence of mutant and wild-type ...
Efeito da administração de esteroides anabólico-androgênicos sobre vias metabólicas e alterações morfológicas no tecido muscular esquelético exercitado
(Universidade Federal de São Carlos, 2021-05-05)
The present study, as a descriptive review, aimed to comprehend the effects of the exogenous anabolic-androgenic administration on metabolic pathways, as well as the physiological modulation of the exercised skeletal muscle ...