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Ovariectomia e treinamento resistido: influência na morfologia e angiogênese do tecido adiposo visceral de ratas
(Universidade Federal de São Carlos, 2014-09-09)
Ovariectomy in animals (surgical removal of ovaries) is a model used to mimic the menopause in women. The ovarian hormone deficiency alters the lipid profile, increases inflammation and the risk of type 2 diabetes mellitus, ...
Efeito do treinamento resistido sobre a atividade enzimática da MMP-2 e antioxidantes no ventrículo esquerdo de ratos obesos
(Universidade Federal de São Carlos, 2013-03-22)
Obesity is associated with increased lipid peroxidation in the myocardium and an increased susceptibility to oxidative damage, which can lead to several cardiovascular risk factors including heart failure, insulin resistance, ...
Alterações agudas no metabolismo energético de ratos submetidos ao exercício resistido em escada
(Universidade Federal de São Carlos, 2012-05-22)
Previous animal s research has shown that many protocols with aimed to mimic human exercise has been used. The endurance protocols are studied very often however, some difficulties are encountered to produce resistance ...
Papel do treinamento físico aeróbio na modulação do balanço pró e antiangiogênico no músculo esquelético de ratos Wistar tratados com dexametasona
(Universidade Federal de São Carlos, 2016-03-29)
Dexamethasone (DEX) is widely used in clinic due to its effectiveness as anti-
inflammatory. Nevertheless, its chronic use may cause unwanted metabolic and
hemodynamic alterations, which contribute for the development ...
Caracterização farmacológica dos efeitos induzidos pelo complexo de rutênio cis-[Ru(H-dcbpy-)2(Cl)(NO2- )] e Nitroprussiato de Sódio na disfunção endotelial
(Universidade Federal de São Carlos, 2016-04-15)
Endothelial dysfunction has been considered a marker for the presence of
cardiovascular disease. It is characterized by decreased release of vasodilatory
factors and increased of vasoconstrictors factors. Nitric oxide ...
Envolvimento do receptor de angiotensina II tipo 1 nas alterações cardiovasculares induzidas pelo estresse crônico : comparação entre estressores homotípicos e heterotípicos
(Universidade Federal de São Carlos, 2016-03-31)
Emotional stress has been recognized as a risk factor for cardiovascular diseases. Nevertheless, the mechanisms involved in the etiology of cardiovascular dysfunctions evoked by stress are still poorly understood. Thus, ...
Os efeitos do treinamento físico, associado ao perindopril, na rigidez arterial de ratos espontaneamente hipertensos
(Universidade Federal de São Carlos, 2019-03-27)
Hypertension (HT) is a complex and multifactorial disease considered one of the main risk factor for cardiovascular diseases. It is maintained mainly by structural changes in vessels that contribute to increase vascular ...
Efeito do bloqueio dos receptores mineralocorticoides da região infra-límbica do córtex pré-frontal medial sobre a tolerância aos efeitos do midazolam em camundongos submetidos ao protocolo de teste e reteste no labirinto em cruz elevado
(Universidade Federal de São Carlos, 2017-05-25)
Several studies have shown that the previous experience (trial 1) to the elevated plus-maze
(EPM) increases the avoidance of the open arms and impairs the anxiolytic-like effect of
midazolam (MDZ), a benzodiazepine-GABAA ...
Expressão de miostatina e folistatina em ratos castrados submetidos a exercício
(Universidade Federal de São Carlos, 2012-07-19)
Myostatin (MSTN) is a negative regulator of skeletal muscle growth, while androgens are strong positive regulators of muscle growth and strength. Follistatin (FS) is a nonrelated protein which inhibits MSTN action. The ...
Avaliação pancreática de animais submetidos à dieta hiperlipídica
(Universidade Federal de São Carlos, 2012-09-04)
The pathogenesis of type 2 diabetes mellitus (DM2) is associated with insulin resistance (IR) and pancreatic β cells (β cells) defect. Adipose tissue modulates metabolism by releasing free fatty acids (FFA), ...