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Estudo comparativo do efeito da temperatura na estabilidade e espectros de bioluminescência das luciferases de Phrixotrix hirtus e outros besouros bioluminescentes
(Universidade Federal de São Carlos, 2019-03-22)
Firefly luciferases have been extensively used as bioanalytical reagents and their cDNAs as reporter genes and bioimaging biosensors. Luciferases of fireflies, “rail-road” worm and "tec-tec" beetles, have different ...
Mecanismos de regulação da via de sinalização Wnt pela E3 ubiquitina ligase SCF(Fbxo7)
(Universidade Federal de São Carlos, 2019-02-22)
SCF complexes are composed by Skp1, Cullin1, Rbx1 and an F-box protein (FBP), which are responsible to give specificity to the complexes, as they interact with substrates, allowing ligation of an ubiquitin molecule to the ...
Isolamento e caracterização de cepas termotolerantes de Saccharomyces cerevisiae e análise da expressão de genes possivelmente envolvidos com a termotolerância
(Universidade Federal de São Carlos, 2018-03-28)
Brazil is the world’s second largest producer of ethanol, which is produced, in our country, from the fermentation of sugarcane sucrose by Saccharomyces cerevisiae yeast. Despite having a high capacity for ethanol production, ...
Efeito modulador do extrato total do Paenibacillus polymyxa RNC-D em macrófagos e Leishmania (Leishmania) amazonensis in vitro
(Universidade Federal de São Carlos, 2018-04-20)
Leishmaniasis is an infection caused by Leishmania gender protozoa. The treatment of the disease is generally problematic, as the drugs used on clinical practice are toxic. One of the paths in the search for new therapeutic ...
Cistatinas recombinantes de cana-de-açúcar : especificidade, produção em biorreator e conservação por liofilização
(Universidade Federal de São Carlos, 2018-03-02)
Phytocystatins are inhibitors of cysteine peptidases found naturally in plants.
Sugarcane cystatins are distinguished by their high inhibitory activity and possible
biotechnological applications. In this work, a comparative ...
Efeito do nocaute da mitofusina 2 sobre a mitocôndria, o retículo endoplasmático e a mitofagia em oócitos murinos
(Universidade Federal de São Carlos, 2018-08-24)
Mitofusins 1 (MFN1) and 2 (MFN2) are transmembrane GTPases present in the outer mitochondrial membrane and involved in the regulation of mitochondrial fusion. Since MFN2 is also present in the membrane of the endoplasmic ...
Validação de kit imunocromatográfico rápido para diagnóstico da Hepatite C
(Universidade Federal de São Carlos, 2019-09-17)
Hepatitis C is an infectious disease caused by the Hepatitis C Virus (HCV) and usually asymptomatic in the acute phase. Globally, an estimated 71 million people are infected with HCV and approximately 400,000 deaths happen ...
Evolução cromossômica e diversidade genética em espécies de peixes da família Arapaimidae (Teleostei: Osteoglossiformes)
(Universidade Federal de São Carlos, 2019-07-12)
The Neotropical region exhibits the largest diversity of freshwater fishes in the world and the demographic history of several taxa is related to the geomorphological and climatic history of this region. Among the ...
Identificação de redes gênicas de coexpressão e dos mecanismos regulatórios associados à composição mineral e qualidade de carne em bovinos
(Universidade Federal de São Carlos, 2019-10-11)
Meat quality and mineral composition are complex traits genetically regulated. Growing evidence suggests that minerals play a central role in regulatory and physiological functions related to meat tenderness and fat ...
Identificação taxonômica, potencial agrícola e biotecnológico de bactérias endofíticas e rizosféricas associadas a Paspalum atratum e P. notatum
(Universidade Federal de São Carlos, 2019-08-02)
The genus Paspalum belongs to the family Poaceae and has several species native to Brazil. The Germplasm Bank of Paspalum of Embrapa Pecuária Sudeste has about 450 accessions of 50 species. Among the conserved accessions, ...