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Montagem e análise taxonômica-funcional de transcriptomas de espécies de cupins brasileiros
(Universidade Federal de São Carlos, 2020-02-28)
Termites (Isoptera) are eusocial insects that stand out for their hierarchical and structural organization, demonstrating complex social behaviors, numerous symbiotic interactions, and a great potential for bioprospecting ...
Evolução e integração de fenótipos complexos em insetos: estudo de caso em Teleopsis Dalmanni (Diptera:Diopsidae) e em espécies de Anastrepha do grupo Fraterculus (Diptera: Tephritidae)
(Universidade Federal de São Carlos, 2018-08-31)
Complex traits are affected by multiple traits and processes, whose interaction shape and determine their evolutionary patterns. This work uses quantitative evolutionary genetic methodologies to understand the evolutionary ...
Deleção oócito-específica da Rad51 em murinos e seu impacto sobre a função mitocondrial e a fertilidade
(Universidade Federal de São Carlos, 2020-02-14)
One of the first signs of aging in humans is the decrease in female fertility, which is
accompanied by a reduction in the expression of proteins that integrate the Double Strand Break
(DSB) repair machinery, such as ...
Prospecção de regiões pleiotrópicas para características complexas relevantes ao melhoramento bovino a partir de GWAS bi-característica
(Universidade Federal de São Carlos, 2019-05-31)
The demand for sustainable beef production systems drives the development of new tools that aim to reduce the production costs and to avoid losses in meat quality. The objective of this study was to identify possible ...
Diversidade genética e estruturação populacional do tatu-canastra (Priodontes maximus) em uma área do Centro-Oeste do Brasil
(Universidade Federal de São Carlos, 2020-03-30)
The giant armadillo, Priodontes maximus, is a neotropical mammal that belongs to the Xenarthra superorder. The species is widely distributed in nine countries in South America. Although its distribution is wide, it occurs ...
Impacto da deleção oócito-específica de Rad51 sobre o DNA mitocondrial e a divisão meiótica em murinos
(Universidade Federal de São Carlos, 2020-02-28)
RAD51 is a protein of eukaryotic organisms, with a central role in the DNA repair pathway by homologous recombination. Its function in the nucleus of somatic cells is well established, being necessary for the maintenance ...
Efeito das enzimas recombinantes de Schistosoma mansoni Hipoxantina-Guanina Fosforibosiltransferase (HGPRT) e Purina Nucleosídeo Fosforilase (PNP) no tratamento da esquistossomose experimental
(Universidade Federal de São Carlos, 2018-02-26)
Schistosomiasis is a disease that affects a large number of people in 78 countries. The
number of cases has increased in recent years and there is no vaccine and new drugs, a
worrying aspect, since there is loss of ...
Aspectos filogeográficos de Leporinus cf. friderici e da distribuição da diversidade genética em Leporinus cf. friderici Paraná e Megaleporinus obtusidens na bacia do Alto Paraná
(Universidade Federal de São Carlos, 2018-10-05)
The megadiversity of the Neotropical ichthyofauna has been associated to recent diversification processes, reflecting in subtle or lacking morphological differentiation between species, challenging the classical taxonomic ...
Determinantes estruturais da bioluminescência vermelha e eficiência catalítica na luciferase de phrixothrix hirtus e seleção de combinação emissora de luz vermelha distante com 6´-amino-análogos de luciferina
(Universidade Federal de São Carlos, 2019-12-06)
Luciferases are the enzymes responsible for bioluminescence. These enzymes catalyze the oxidation of luciferins, in which the energy is released in the form of light with high efficiency. The luciferases fireflies from ...
Desenvolvimento de biossensores raciométricos bioluminescentes de ph e metais divalentes baseados na engenharia da região sensível ao pH nas luciferases de vagalumes
(Universidade Federal de São Carlos, 2017-12-01)
Bioluminescence, the emission of visible light by living organisms is widely used in biosensors. Firefly luciferases and genes are among the most used reporter gene in bioluminescent biosensors. Firefly luciferases are ...