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Síntese de porfirinas contendo grupos do tipo uracil fundidos nas posições β-pirrólicas
(Universidade Federal de São Carlos, 2014-07-28)
In this work the synthesis of new porphyrin derivatives were proposed. The preparations of new compounds containing uracil groups at β-pirrolic position were studied based on their interest in organics synthesis. We ...
Obtenção de derivados de compostos isolados de Zingiber officinale por biotransformação e semi-síntese e avaliação frente à cisteinil-proteases
(Universidade Federal de São Carlos, 2016-07-01)
Several aromatic polyketide derivatives from Ginger (Zingiber officinale), like zingerone,
6-gingerol and 6-shogaol were obtained by biocatalytic reactions and semi-synthesis and
both their antifungal and cysteine-proteinase ...
Busca por novos metalofármacos contra doenças negligenciadas (malária, doença de chagas e leishmaniose)
(Universidade Federal de São Carlos, 2012-07-13)
Leishmaniasis, Chagas disease and malaria are neglected parasitic diseases responsible for high mortality in tropical low-income countries. Due to the lack of vaccines and of safe, effective and affordable treatments, there ...
A aprendizagem de catálise enzimática por meio de casos: proposta para o ensino de química
(Universidade Federal de São Carlos, 2018-11-09)
The fundamental aim of provoking innovative forms of knowledge construction in Chemistry during basic education requires the instrumentalization of strategies that can show re-significances of pedagogical practices and ...
Estudo metabolômico dos constituintes voláteis de algodoeiro submetido à interações bióticas e abióticas e mecanismos de indução de resistência
(Universidade Federal de São Carlos, 2020-02-17)
Plants have developed several defense strategies against herbivory, one of which is the response of induced defenses that represents the biosynthesis of phytotoxic molecules through attack. Plant resistance mechanisms can ...
Avaliação da atividade bactericida e antineoplásica de novos complexos de Ag(I) contendo semicarbazonas e trifenilfosfina como ligantes
(Universidade Federal de São Carlos, 2019-09-27)
Title: EVALUATION OF BACTERIAL ACTIVITY AND ANTINEOPLASTIC OF NEW Ag(I) COMPLEXES CONTAINING SEMICARBAZONES AND TRIPHENYLPHOSPHINES AS LIGANDS. The present work aimed to evaluate the influence of ligands triphenylphosphine ...
Papaína imobilizada em partículas magnéticas: novos modelos de triagem de ligantes
(Universidade Federal de São Carlos, 2019-03-29)
Cathepsins, human lysosomal enzymes, are associated with the development of various diseases, and cruzaine is an important enzyme in the development of the protozoan Trypanosoma cruzi, causes Chagas' disease. Cysteine ...
Síntese e caracterização de vanadatos de prata e formação de nanopartículas de prata por eletro-Irradiação
(Universidade Federal de São Carlos, 2018-02-19)
Due to its physico-chemical, bactericidal and photocatalytic properties, Silver vanadium oxides (SVOs) have attracted increasing attention due to their excellent physicochemical properties and diverse applications. The aim ...
Synthesis of N-heterocycles and building blocks using multicomponent, photochemical and electrochemical approaches
(Universidade Federal de São Carlos, 2020-02-17)
Multicomponent reactions and protocols mediated by light and electrochemistry are powerful tools for modern organic synthesis. Moreover, they obey several principles of green chemistry such as atom economy, catalysis, waste ...
Desenvolvimento de fibras compósitas ultrafinas de policaprolactona, pectina e zeólita faujasita para acondicionamento de cloxacilina
(Universidade Federal de São Carlos, 2020-03-27)
Bovine mastitis and hoof diseases are infections responsible for great economic losses in the Brazilian agricultural sector. Such losses are associated with a reduction in milk and meat production leading to extreme cases ...