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Níveis de ADAM10 no líquido cefalorraquidiano e soro de indivíduos com doença de Alzheimer
(Universidade Federal de São Carlos, 2018-11-12)
Researchers have pointed out that the identification of ADAM10 as a biomarker can be an important tool to aid in the clinical diagnosis of AD. The proposal of ADAM10 as a biomarker occurs because it is involved in different ...
Níveis da secretase ADAM10 em idosos com diabetes mellitus tipo 2 e doença de Alzheimer
(Universidade Federal de São Carlos, 2022-02-17)
Alzheimer's disease (AD) is a gradual and progressive neurodegenerative disease characterized
by predominant cortical atrophy in the medial temporal lobe and microscopically extensive
neuronal losses and deposits called ...
A Desintegrina e Metaloproteinase 10 (ADAM10) como biomarcadora para a doença de Alzheimer: uma revisão sistemática
(Universidade Federal de São Carlos, 2022-08-08)
Introduction: Studies have shown that Disintegrin and Metalloproteinase 10 (ADAM10) is the
main α-secretase in the non-amyloidogenic cleavage of amyloid precursor protein (APP). ADAM10
prevents the production of β-amyloid ...