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Fitocistatinas: caracterização bioquímica e aplicação na transformação genética de cana-de-açúcar
(Universidade Federal de São Carlos, 2018-02-27)
Cystatins are tight-binding, competitive cysteine-peptidase inhibitors. In plants, these proteins are part of natural defense mechanism, regulating endogenous and exogenous peptidases. In humans, cystatins are responsible ...
Clonagem e expressão heteróloga de proteínas estruturais (C, prM, E) de Zika Virus (ZIKV)
(Universidade Federal de São Carlos, 2018-08-31)
Viruses are organisms which depend on the host cellular machinery to replicate,
and are relevant to human, livestock and plant health. The modern threat of emerging
pandemics is pressing and, in this scenario, Zika Virus ...
Validação de kit imunocromatográfico rápido para diagnóstico da Hepatite C
(Universidade Federal de São Carlos, 2019-09-17)
Hepatitis C is an infectious disease caused by the Hepatitis C Virus (HCV) and usually asymptomatic in the acute phase. Globally, an estimated 71 million people are infected with HCV and approximately 400,000 deaths happen ...
Desenvolvimento de biossensores raciométricos bioluminescentes de ph e metais divalentes baseados na engenharia da região sensível ao pH nas luciferases de vagalumes
(Universidade Federal de São Carlos, 2017-12-01)
Bioluminescence, the emission of visible light by living organisms is widely used in biosensors. Firefly luciferases and genes are among the most used reporter gene in bioluminescent biosensors. Firefly luciferases are ...
Análise dos transcriptomas de Paspalum notatum Flúggé e Paspalum vaginatum Swartz em condição de déficit hídrico
(Universidade Federal de São Carlos, 2020-02-19)
Drought is one of the abiotic stresses that most affect plant growth and productivity. Grasses of the genus Paspalum are used successfully in pastures and lawns, and some ecotypes of Paspalum notatum (bahiagrass) have good ...
Atividades anti-nematoides dos óleos essenciais de Petroselinum crispum, Ruta graveolens e Thymus vulgaris no modelo nematoide Caenorhabditis elegans
(Universidade Federal de São Carlos, 2019-05-23)
The nematode parasites represent a major public health problem and several economic loss in the agricultural sector. The study of essential oils in the model organism Caenorhabditis elegans allows to identify the nematicidal ...
Caracterização fenotípica e molecular dos mecanismos de resistência aos beta-lactâmicos em linhagens clínicas de Klebsiella pneumoniae isoladas do Amazonas
(Universidade Federal de São Carlos, 2018-10-25)
Klebsiella pneumoniae resistant to beta-lactams are present in hospitals worldwide and reduce treatment alternatives. In this study, 40 K. pneumoniae isolates were characterized. All of them were resistant to beta-lactam ...
Caracterização funcional e bioquímica do fator de transcrição rlmA e da interação de PkcA e Hsp90 no fungo Aspergillus fumigatus
(Universidade Federal de São Carlos, 2017-12-18)
Aspergillus fumigatus is an opportunistic human pathogen that causes systemic infections, including invasive pulmonary aspergillosis in immunocompromised individuals. Survival of this fungus is highly dependent on the cell ...
Efeitos de carboidratos no desempenho, na digestão e no metabolismo de matrinxã (Brycon amazonicus) e híbridos de pintado (Pseudoplatystoma corruscans x Pseudoplatystoma fasciatum) em um período curto de alimentação
(Universidade Federal de São Carlos, 2012-01-13)
Improvements in fish farming production require continuous research in nutrient formulation and diet technology. Feeding is the most important handling daily practiced by fish farmers and diets must supply the nutritional ...
Clonagem e caracterização das isoformas de luciferases de lanternas e corpo gorduroso do vagalume Aspisoma lineatum (Lampyridae: Cratomorphini): origem estrutural e evolutiva das luciferases pH-sensitivas mais eficientes à partir de ancestrais pH-insensitivas
(Universidade Federal de São Carlos, 2020-10-31)
Firefly luciferases emit yellow-green light with high efficiency at physiological pH. However, under acidic conditions, in the presence of heavy metals or high temperatures, they emit red light. To understand the structural ...