Search
Now showing items 21-30 of 252
Deleção oócito-específica da Rad51 em murinos e seu impacto sobre a função mitocondrial e a fertilidade
(Universidade Federal de São Carlos, 2020-02-14)
One of the first signs of aging in humans is the decrease in female fertility, which is
accompanied by a reduction in the expression of proteins that integrate the Double Strand Break
(DSB) repair machinery, such as ...
Prospecção de regiões pleiotrópicas para características complexas relevantes ao melhoramento bovino a partir de GWAS bi-característica
(Universidade Federal de São Carlos, 2019-05-31)
The demand for sustainable beef production systems drives the development of new tools that aim to reduce the production costs and to avoid losses in meat quality. The objective of this study was to identify possible ...
Diversidade genética e estruturação populacional do tatu-canastra (Priodontes maximus) em uma área do Centro-Oeste do Brasil
(Universidade Federal de São Carlos, 2020-03-30)
The giant armadillo, Priodontes maximus, is a neotropical mammal that belongs to the Xenarthra superorder. The species is widely distributed in nine countries in South America. Although its distribution is wide, it occurs ...
Efeito das enzimas recombinantes de Schistosoma mansoni Hipoxantina-Guanina Fosforibosiltransferase (HGPRT) e Purina Nucleosídeo Fosforilase (PNP) no tratamento da esquistossomose experimental
(Universidade Federal de São Carlos, 2018-02-26)
Schistosomiasis is a disease that affects a large number of people in 78 countries. The
number of cases has increased in recent years and there is no vaccine and new drugs, a
worrying aspect, since there is loss of ...
Aspectos filogeográficos de Leporinus cf. friderici e da distribuição da diversidade genética em Leporinus cf. friderici Paraná e Megaleporinus obtusidens na bacia do Alto Paraná
(Universidade Federal de São Carlos, 2018-10-05)
The megadiversity of the Neotropical ichthyofauna has been associated to recent diversification processes, reflecting in subtle or lacking morphological differentiation between species, challenging the classical taxonomic ...
Desenvolvimento de biossensores raciométricos bioluminescentes de ph e metais divalentes baseados na engenharia da região sensível ao pH nas luciferases de vagalumes
(Universidade Federal de São Carlos, 2017-12-01)
Bioluminescence, the emission of visible light by living organisms is widely used in biosensors. Firefly luciferases and genes are among the most used reporter gene in bioluminescent biosensors. Firefly luciferases are ...
Evolução cromossômica na família Lebiasinidae (Teleostei, Characiformes), com enfoque em espécies do gênero Lebiasina
(Universidade Federal de São Carlos, 2020-02-06)
The Lebiasinidae family is composed by seven genus of small freshwater fishes that can be found in small rivers of Central and South America. Members of this family presents a great diversity in form and body color, but ...
Efeitos citotóxicos e genotóxicos de uma nova nanopartícula de titânio de interesse industrial - in vitro
(Universidade Federal de São Carlos, 2020-02-18)
Titanium dioxide nanoparticles (TiO2 NP) are included as one of the most used nanomaterials by industries in general; it is applied in coatings, pigments, and paints for its ability to offer opacity and brightness, in ...
Eficácia da instilação de células da linhagem MB49 e gel polimérico termorreversível na imunização contra o carcinoma urotelial de bexiga
(Universidade Federal de São Carlos, 2020-09-24)
Among the various types of malignant neoplasms, those originating in the bladder can be considered highly impactful due to their prevalence and high recurrence rates, demonstrating the importance of studies involving new ...
Investigação dos mecanismos envolvidos na herança mitocondrial: o papel da dinâmica mitocondrial
(Universidade Federal de São Carlos, 2020-10-08)
Diseases caused by mutations in mitochondrial DNA (mtDNA) are the most common genetic diseases in humans. Despite this, there is no effective treatment for these diseases and the mechanisms of inheritance are not fully ...