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Expressão de miostatina e folistatina em ratos castrados submetidos a exercício
(Universidade Federal de São Carlos, 2012-07-19)
Myostatin (MSTN) is a negative regulator of skeletal muscle growth, while androgens are strong positive regulators of muscle growth and strength. Follistatin (FS) is a nonrelated protein which inhibits MSTN action. The ...
Remodelamento da matriz extracelular e respostas cardíacas funcionais em ratos idosos submetidos a treinamento resistido
(Universidade Federal de São Carlos, 2016-03-04)
INTRODUCTION: It is well documented that aging causes morphological and functional alterations in the heart. Cardiac ECM remodeling is one event of structural changes in left ventricle (LV), which is modulated by MMPs/TIMPs ...
Ovariectomia e treinamento resistido: influência na morfologia e angiogênese do tecido adiposo visceral de ratas
(Universidade Federal de São Carlos, 2014-09-09)
Ovariectomy in animals (surgical removal of ovaries) is a model used to mimic the menopause in women. The ovarian hormone deficiency alters the lipid profile, increases inflammation and the risk of type 2 diabetes mellitus, ...
Estudo do papel da ADAM9 na disseminação tumoral via sistema linfático: possível alvo farmacológico
(Universidade Federal de São Carlos, 2014-12-12)
Tumor spreading occurs mainly by two pathways: through blood vessels and by lymphatic vessels, but the last is preferred by breast tumor cells. Some proteins are involved in cell adhesion and proteolysis, causing metastasis, ...
Etanol e suas associações : efeitos comportamentais e cardiovasculares
(Universidade Federal de São Carlos, 2016-09-26)
Alcohol abuse is a worldwide problem with concomitant medical, social
and economic costs. In Brazil, epidemiological data show an increase in the
abuse of illicit and licit drugs, such as ethanol and steroids. Studies ...
Efeitos do treinamento resistido sobre o metabolismo lipídico, a inflamação e a morfometria do tecido adiposo de ratas ovariectomizadas
(Universidade Federal de São Carlos, 2013-06-06)
Visceral obesity is an important risk factor cardiovascular diseases. After menopause, fat distribution shifts to visceral depots leading to lipid metabolism disorders and chronic lowgrade inflammation. Resistance training ...
Diferentes respostas à alternagina-c, uma proteína tipo desintegrina, em fibroblastos, células tumorais de mama e células endoteliais in vitro
(Universidade Federal de São Carlos, 2013-12-10)
Matrix metalloproteinases (MMPs) are key factors in tumor progression that allow tumor cells to modify the extracellular matrix (ECM) and to release cytokines, growth factors being activated by cell surface molecules such ...
Perfil dermatoglífico, somatotípico e fisiológico de atletas de elite do rafting
(Universidade Federal de São Carlos, 2016-12-14)
Rafting is a modality that is summed up in the descent of rivers in inflatable boats, in which the members of the boat paddle under the command of an instructor responsible for the orientation of the group during the course, ...
Efeito da temperatura sobre as interações cardiorrespiratórias em sapos Rhinella schneideri
(Universidade Federal de São Carlos, 2016-10-26)
For adequate blood supply to match metabolic demand, vertebrates regulate blood
pressure (BP) in order to maintain adequate perfusion of target organs avoiding ischemia and
tissue damage like edema. Effective short-term ...
Efeito de três diferentes protocolos de treinamento, resistido, aeróbico e combinado, na modulação da omentina e vaspina em modelo experimental de diabetes mellitus tipo 2
(Universidade Federal de São Carlos, 2016-08-08)
This study aims to determine the effects of three different exercise modalities (aerobic,
strength and combined) on the production of the adipokines Omentin and Vaspin in obese
mice with type 2 diabetes mellitus. To this ...