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Ativação da GCs no endotélio como estratégia para reverter e/ou prevenir a disfunção endotelial
(Universidade Federal de São Carlos, 2019-05-10)
Introduction: The vascular endothelium presents an important protective function against cardiovascular diseases, and the release of NO has a central role in this protection. Reduction of NO bioavailability and decreased ...
Efeito da fotobiomodulação na pressão arterial de ratos hipertensos
(Universidade Federal de São Carlos, 2018-06-28)
Introduction: Hypertension affects a quarter of the Brazilian adult population and is the main risk factor for myocardial infarction, stroke and chronic kidney disease, and has been considered a global health problem. ...
Envolvimento da neurotransmissão nitrérgica do núcleo leito da estria terminal (NLET) nas respostas cardiovasculares ao estresse em ratos: interação com mecanismos glutamatérgicos e noradrenérgicos locais
(Universidade Federal de São Carlos, 2018-04-02)
The aim of the present study was to assess an interaction between nitrergic neurotransmission within the bed nucleus of the stria terminalis (BNST) with local glutamatergic and noradrenergic neurotransmissions in control ...
Sensibilização comportamental ao etanol em camundongos: avaliação da expressão da proteína (delta)FosB e possíveis efeitos da lateralização na via mesocorticolímbica
(Universidade Federal de São Carlos, 2019-05-06)
One of the main challenges of ethanol addiction research is to unveil the brain changes responsible for the transition from recreational drug use to addiction. In this context, behavioral sensitization has been used as a ...
O bloqueio dos receptores NMDA ou CRF1 no núcleo intersticial da estria terminal impede a ansiogênese induzida pela ativação nitrérgica do córtex pré-frontal medial e derrota social em camundongos
(Universidade Federal de São Carlos, 2019-09-20)
Nitric oxide (NO) release in the right medial prefrontal cortex (RmPFC) produces anxiogenesis. In the bed nucleus of the stria terminalis (BNST), a region that receives neuronal projections from the mPFC, NO also provokes ...
Efeitos de complexos metálicos de cobre no câncer de mama triplo negativo
(Universidade Federal de São Carlos, 2019-09-06)
Breast cancer is the second most common type in the world and can be considered a disease with good prognosis if diagnosed early and treated timely. The treatment of breast cancer aims to increase survival and improve the ...
Estudo da participação da neurotransmissão CRFérgica do núcleo leito da estria terminal (NLET) no controle da função cardiovascular em ratos: envolvimento nas alterações cardiovasculares induzidas pelo estresse crônico variado?
(Universidade Federal de São Carlos, 2020-03-06)
The aim of the present study was to investigate the role of CRFergic neurotransmission into bed nucleus of stria terminalis (BNST) on cardiovascular function. We observed that bilateral microinjection of the selective CRF1 ...
Avaliação da participação dos receptores N-metil-D-aspartato (NMDA) e do Fator de Liberação de Corticotropina (CRF) nos efeitos aversivos do óxido nítrico no núcleo intersticial da estria terminal de camundongos
(Universidade Federal de São Carlos, 2015-05-28)
It has been shown that the bed nucleus of the stria terminalis (BNST) of rats contains nitrergic neurons, which are activated during animal exposure to aversive stimuli. BNST is also populated by glutamatergic and ...
Alterações cardiovasculares induzidas pela obesidade : envolvimento do sistema reninaangiotensina no núcleo do trato solitário
(Universidade Federal de São Carlos, 2016-02-01)
In the last decades, obesity has become a worldwide epidemy. Excess of adipose tissue favors the development of associated diseases such as hypertension, obstructive sleep apnea and type II diabetes. Data from the literature ...
Envolvimento de neurotransmissões angiotensinérgicas no núcleo medial da amídala nas respostas cardiovasculares e ansiogênica ao estresse de restrição em ratos
(Universidade Federal de São Carlos, 2020-09-04)
Limbic structures participate in the control of physiological responses related to stress, and the medial amigdaloid nucleus (MeA) has been demonstrated as an area of the central nervous system involved in the control these ...