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Aplicação de técnicas de análise de imagens na quantificação da concentração celular no cultivo de células de inseto.
(Universidade Federal de São Carlos, 2004-04-26)
Paradoxally, in spite of the cellular concentration to be the most important variable
in a bioprocess, in practice is the less monitored as a consequence of the experimental
difficulty found in its quantification in an ...
Inovações na produção de antibióticos β-lactâmicos
(Universidade Federal de São Carlos, 2009-04-02)
The industrial production of 6-APA includes: (1) cultivation of Penicillium chrysogenum; (2) extraction with organic solvents, (3) crystallization; (4) penicillin hydrolysis by immobilized penicillin acylase; (5) extraction ...
Contribuição ao desenvolvimento de metodologia para detecção de desintegrina recombinante produzida em cultivos de células CHO-K1.
(Universidade Federal de São Carlos, 2004-06-25)
Disintegrins are proteins present in the poison of serpents that have been calling the pharmaceutical industry attention due to their capacity to prevent the progression of cancerous cells. A receiving key-protein called ...
Avaliação de partículas poliméricas como material suporte em reator anaeróbio de leito fluidizado no tratamento de fenol.
(Universidade Federal de São Carlos, 2005-03-24)
This work had as objective studies of the biofilms formation in polymerics
particles used as material supports in anaerobic fluidized-bed reactors. Three
polymerics supports were tested: polystyrene, PET and PVC, which ...
Avaliação de fontes de carbono e condições de indução na expressão de canacistatina em Escherichia coli BL21 (DE3)
(Universidade Federal de São Carlos, 2006-03-30)
Canecystatin (CC) is a competitive and reversible protease inhibitor which blocks the proteolytic enzymes activities of insets, fungus e nematodes, prejudicing thus the growth, development and reproduction from these ...
Aplicação da lógica fuzzi na produção de penicilina G Acilase em cultivos de Bacillus megaterium
(Universidade Federal de São Carlos, 2003-07-28)
Penicillin G acylase (PGA) is an important enzyme for the pharmaceutical industry. This enzyme has industrial use in the hydrolysis of penicillin G to obtain 6-aminocephalosporanic acid (6-APA), essential intermediate for ...
Produção recombinante e estudos funcionais de uma cisteíno peptidase de Xanthomonas citri subspécie citri
(Universidade Federal de São Carlos, 2009-04-29)
The citrus canker disease is caused by a phytopathogenic bacterium Xanthomonas citri ssp. citri (Xac). The common symptoms are defoliation, twig die-back and premature fruit drop. The infection process of this bacterium ...
Avaliação de formas de preparação de estoques de trabalho na preservação de Streptomyces clavuligerus visando a produção de ácido clavulânico
(Universidade Federal de São Carlos, 2008-08-28)
A great deal of microbiological and genetic research in the pharmaceutical industry is directed towards the development of effective strategies in the handling of microorganisms
seeking the production of antibiotics that ...
Estabelecimento de meios de cultura para o cultivo de Streptomyces isolados de sedimento marinho
(Universidade Federal de São Carlos, 2009-10-16)
Microorganisms represent an important source for production of bioactive metabolites for diverse applications. The production of these substances is directly related to the culture medium associated with sources of carbon ...
Purificação e caracterização bioquímica de substâncias bioativas produzidas por endofítico isolado de Prunus spp.
(Universidade Federal de São Carlos, 2009-03-13)
Bioprospective studies of endophytic microorganisms for biotechnological applications are essentials to discovery new substances, which can be used in different areas. Endophytes represent an excellent source of bioactive ...