Browsing by CNPq Subject "CIENCIAS BIOLOGICAS::BIOQUIMICA::QUIMICA DE MACROMOLECULAS"
Now showing items 1-7 of 7
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Docking molecular e interações não-covalentes de compostos originais derivados de 2-aril-oxazolinas em enzimas de Candida spp.
(Universidade Federal de São Carlos, UFSCar, Programa de Pós-Graduação em Biotecnologia - PPGBiotec, Câmpus São Carlos, 23/08/2019)Candidiasis is a mycosis caused by fungi of the genus Candida spp. It affects up to 50% of the world's population and may progress to candidaemia, leading to death in up to a half of patients. Commercial drugs used in its ... -
Estudos bioquímicos e cinéticos de acetilcolinesterases de formigas cortadeiras (Atta sexdens)
(Universidade Federal de São Carlos, UFSCar, Programa de Pós-Graduação em Química - PPGQ, Câmpus São Carlos, 29/09/2017)Acetylcholinesterase (AChE) (EC 3.1.1.7) is the enzyme responsible for catalyzing the hydrolysis of the neurotransmitter acetylcholine leading to the release of acetate and choline. In insects, acetylcholine is one of the ... -
Avaliação dos efeitos de revestimentos naturais na conservação de carne bovina resfriada e embalada a vácuo
(Universidade Federal de São Carlos, UFSCar, Programa de Pós-Graduação em Biotecnologia - PPGBiotec, Câmpus São Carlos, 30/10/2015)Brazil is the world’s second largest producer and exporter of bovine fresh meat, what in 2014 accounted for about US$23.31 billion in Gross Value of Production (GVP) in a market of US$62.97 billion per year, generating ... -
Aplicação do mapeamento vetorial para biomoléculas
(Universidade Federal de São Carlos, UFSCar, Programa de Pós-Graduação em Biotecnologia - PPGBiotec, Câmpus São Carlos, 09/10/2017)The main focus of this work was to study two types of non-covalent interactions: π interactions and hydrogen bonds. This type of study is necessary when one wants to analyze, for example, enzyme-ligand or DNA-ligand ... -
Nanoformulação do [10]-Gingerol em células de câncer de mama triplo negativo
(Universidade Federal de São Carlos, UFSCar, , Câmpus São Carlos, 08/10/2020)Breast cancer is the neoplasm that most affects women worldwide and can be classified into different types. Among them, triple negative breast cancer (TN) is characterized by not having hormone receptors, nor receptors for ... -
Análise in silico de um novo composto possível inibidor de ciclooxigenase 2 utilizando docking molecular
(Universidade Federal de São Carlos, UFSCar, , Câmpus São Carlos, 04/01/2021)This work describes the study of the formation of complexes between the enzyme cyclooxygenase (COX-2) and some of its inhibitors. For this purpose, the known inhibitors celecoxib (CEL), rofecoxib (RCX) and Korean 21 and ... -
Expressão, purificação e caracterização estrutural dos mutantes truncados da Hsp70-escort protein 1 humana
(Universidade Federal de São Carlos, UFSCar, , Câmpus São Carlos, 15/02/2024)The 70 kDa Heat shock protein (Hsp70 or HSPA in humans) is a highly conserved family of molecular chaperones that is expressed in various cellular compartments and is associated with several pathologies, including ...