Browsing by Subject "Fração de cura"
Now showing items 1-17 of 17
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Modelos de fração de cura com fragilidade inflacionado de zero sob diferentes esquemas de ativação
(Universidade Federal de São Carlos, UFSCar, Programa Interinstitucional de Pós-Graduação em Estatística - PIPGEs, Câmpus São Carlos, 22/08/2023)In this doctoral thesis, the proposed methodology is based on zero-inflated survival data to deal with situations where there is a fraction of inflated (or adjusted) zeros and cured cases considering different activation ... -
Defective models for cure rate modeling
(Universidade Federal de São Carlos, UFSCar, Programa de Pós-Graduação em Estatística - PPGEs, Câmpus São Carlos, 01/04/2016)Modeling of a cure fraction, also known as long-term survivors, is a part of survival analysis. It studies cases where supposedly there are observations not susceptible to the event of interest. Such cases require special ... -
Estimação paramétrica do modelo de mistura padrão com fragilidade aditiva gama: aplicação a dados de câncer de mama
(Universidade Federal de São Carlos, UFSCar, , Câmpus São Carlos, 16/09/2022)Breast cancer is caused by the uncontrolled growth of abnormal cells in the breast, which multiply rapidly, aggressively and uncontrollably. This disease affects women all over the world, both in developed and underdeveloped ... -
Um estudo dos modelos de sobrevivência de longa duração LIGcr e GEPGWcr
(Universidade Federal de São Carlos, UFSCar, Programa Interinstitucional de Pós-Graduação em Estatística - PIPGEs, Câmpus São Carlos, 04/10/2022)In this work we study two long-term survival models denomined Logaritmic Inverse Gaussian cure rate (LIGcr) model and Geometric Exponentiated Power Generalized Weibull cure rate (GEPGWcr) model. Both models take into ... -
Modelos de sobrevivência induzidos por fragilidade discreta com fração de cura e riscos proporcionais
(Universidade Federal de São Carlos, UFSCar, Programa Interinstitucional de Pós-Graduação em Estatística - PIPGEs, Câmpus São Carlos, 21/10/2022)This work presents two new survival models induced by discrete frailty with unobserved heterogeneity and proportional hazards structure, for lifetime data. The first model consider the discrete frailty variable with Katz ... -
Testes de superioridade para modelos de chances proporcionais com e sem fração de cura
(Universidade Federal de São Carlos, UFSCar, Programa Interinstitucional de Pós-Graduação em Estatística - PIPGEs, Câmpus São Carlos, 24/10/2017)Studies that prove the superiority of a drug in relation to others already existing in the market are of great interest in clinical practice. Based on them the Brazilian National Agency of Sanitary Surveillance (ANVISA) ... -
Modelos de sobrevivência com fração de cura usando um termo de fragilidade e tempo de vida Weibull modificada generalizada
(Universidade Federal de São Carlos, UFSCar, Programa de Pós-Graduação em Estatística - PPGEs, , 24/02/2011)In survival analysis, some studies are characterized by having a significant fraction of units that will never suffer the event of interest, even if accompanied by a long period of time. For the analysis of long-term data, ... -
Modelo de mistura padrão com tempos de vida exponenciais ponderados
(Universidade Federal de São Carlos, UFSCar, Programa de Pós-Graduação em Estatística - PPGEs, , 05/03/2010)In this work, we brie_y introduce the concepts of long-term survival analysis. We dedicated ourselves exclusively to the standard mixture cure model from Boag (1949) and Berkson & Gage (1952), showing its deduction and ... -
Modelos de sobrevivência na presença de eventos recorrentes e longa duração
(Universidade Federal de São Carlos, UFSCar, Programa de Pós-Graduação em Estatística - PPGEs, , 05/03/2010)In this thesis it is proposed to analyze recurrent event data, recurrent event data with cure fraction and recurrent event data with censoring and competing causes. For the recurrent event data analysis it is proposed a ... -
Modelo de mistura padrão com fragilidade gama: aplicação a dados de melanoma
(Universidade Federal de São Carlos, UFSCar, , Câmpus São Carlos, 26/01/2024)Cancer is a malignant disease that can affect several organs. When it spreads throughout the body and reaches other organs, it is called metastasis, and this is the leading cause of cancer-related death. Although skin ... -
Modelagens estatística para dados de sobrevivência bivariados : uma abordagem bayesiana
(Universidade Federal de São Carlos, UFSCar, Programa Interinstitucional de Pós-Graduação em Estatística - PIPGEs, Câmpus São Carlos, 31/03/2017)The frailty models are used to model the possible associations between survival times. Another alternative developed for modeling the dependence between multivariate data is the use of models based on copulas functions. In ... -
Novos modelos de sobrevivência com fração de cura baseados no processo da carcinogênese
(Universidade Federal de São Carlos, UFSCar, Programa de Pós-Graduação em Estatística - PPGEs, , 03/05/2012)In this dissertation we propose new models for survival with cure fraction to describe the biological mechanism of the event of interest (cancer) in studies of carcinogenesis in the presence of competing causes latent ... -
Extensões dos modelos de sobrevivência referente a distribuição Weibull
(Universidade Federal de São Carlos, UFSCar, Programa de Pós-Graduação em Estatística - PPGEs, , 07/03/2014)In this dissertation, two models of probability distributions for the lifetimes until the occurrence of the event produced by a specific cause for elements in a population are reviewed. The first revised model is called ... -
Família Kumaraswamy-G para analisar dados de sobrevivência de longa duração
(Universidade Federal de São Carlos, UFSCar, Programa Interinstitucional de Pós-Graduação em Estatística - PIPGEs, , 25/02/2015)In survival analysis is studied the time until the occurrence of a particular event of interest and in the literature, the most common approach is parametric, where the data follow a specific probability distribution. ... -
Parametric and semi-parametric cure rate models with spatial frailties for interval-censored data
(Universidade Federal de São Carlos, UFSCar, Programa de Pós-Graduação em Estatística - PPGEs, Câmpus São Carlos, 31/05/2016)In this thesis, we extend some flexible cure rate models, such as the geometric, negative binomial and power series cure rate models, to allow for spatial correlations by including spatial frailties for the interval ... -
Modeling survival data based on a reparameterized weighted Lindley distribution
(Universidade Federal de São Carlos, UFSCar, Programa Interinstitucional de Pós-Graduação em Estatística - PIPGEs, Câmpus São Carlos, 24/06/2022)In this work, we propose different statistical modeling for survival data based on a reparameterized weighted Lindley distribution. Initially, we present this distribution and study its mathematical properties, maximum ... -
Novas modelagens de risco aditivo com fragilidade para análise de dados de sobrevivência
(Universidade Federal de São Carlos, UFSCar, Programa Interinstitucional de Pós-Graduação em Estatística - PIPGEs, Câmpus São Carlos, 01/03/2024)Survival analysis emerges as a valuable statistical area for examining the time until the occurrence of events of interest. Several models were designed and applied in different areas such as: Medicine, Engineering, ...