Browsing by Subject "Metastasis"
Now showing items 1-9 of 9
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Efeitos antitumorais e antimetastáticos de novos complexos de rutênio em células de câncer de mama
(Universidade Federal de São Carlos, UFSCar, Programa Interinstitucional de Pós-Graduação em Ciências Fisiológicas - PIPGCF, Câmpus São Carlos, 29/04/2016)Brazil and the world are passing through demographic changes as consequences of population urbanization, industrialization and advances in science and technology. This process, associated with the transformation of ... -
Inibição da integrina αvβ3 em cultura celular 3D de células tumorais e endoteliais em ambiente hipóxico utilizando a desintegrina recombinante DisBa-01
(Universidade Federal de São Carlos, UFSCar, , Câmpus São Carlos, 11/11/2022)Breast cancer has a high global incidence, it was the most fatal type of cancer in 2020, When 66,280 new cases were estimated just in Brazil. The main problems associated with tumors are related to their metastatic behavior, ... -
Avaliação da atividade antitumoral in vitro e in vivo de novos complexos de rutênio contendo ácido salicílico e derivados
(Universidade Federal de São Carlos, UFSCar, Programa Interinstitucional de Pós-Graduação em Ciências Fisiológicas - PIPGCF, Câmpus São Carlos, 30/04/2021)Cancer is a term used for diseases in which abnormal cells divide uncontrolled, spread, and invade other tissues through the blood and lymphatic systems. Breast cancer is one of the most common and with higher mortality ... -
Papel das integrinas αvβ3 e α5β1 na migração de células de tumor de mama triplo negativo e células endoteliais em hipóxia
(Universidade Federal de São Carlos, UFSCar, Programa de Pós-Graduação em Genética Evolutiva e Biologia Molecular - PPGGEv, Câmpus São Carlos, 14/04/2022)Breast tumors show high incidence and mortality for female oncologic cases in 2020. Tumor microenvironment presents several elements, such as extracellular matrix (ECM). ECM proteins bind to cells through receptors such ... -
Silenciamento do gene itgb3 de células de tumor de mama murino triplo negativo (4T1BM2)
(Universidade Federal de São Carlos, UFSCar, , Câmpus São Carlos, 14/09/2022)Breast cancer is the most recurrent type of tumor in the world, surpassing lung cancer, according to data published in 2021 by the World Health Organization (WHO). When tumor cells spread or invade nearby or distant tissues, ... -
Estudo do papel da ADAM9 na disseminação tumoral via sistema linfático: possível alvo farmacológico
(Universidade Federal de São Carlos, UFSCar, Programa Interinstitucional de Pós-Graduação em Ciências Fisiológicas - PIPGCF, , 12/12/2014)Tumor spreading occurs mainly by two pathways: through blood vessels and by lymphatic vessels, but the last is preferred by breast tumor cells. Some proteins are involved in cell adhesion and proteolysis, causing metastasis, ... -
Papel do domínio desintegrina da ADAM9 humana na modulação da migração e invasão de células tumorais
(Universidade Federal de São Carlos, UFSCar, Programa de Pós-Graduação em Genética Evolutiva e Biologia Molecular - PPGGEv, , 25/02/2011)Cancer metastasis is the major cause of death, consequently studies to understand the molecular mechanisms involved in this process are essential to the knowledge of this disease. Cell migration and invasion are part of ... -
Eficácia do [10]-gingerol contra metástases de câncer de mama : estudos in vitro e in vivo em camundongos
(Universidade Federal de São Carlos, UFSCar, Programa de Pós-Graduação em Genética Evolutiva e Biologia Molecular - PPGGEv, Câmpus São Carlos, 20/03/2015)Breast cancer is the leading cause of death in Brazil and worldwide, between the types of cancer, triple negative TNBC (Triple Negative Breast Cancer), which do not express hormone receptors, represents 20% of the cases ... -
Efeitos de complexos metálicos de cobre no câncer de mama triplo negativo
(Universidade Federal de São Carlos, UFSCar, Programa Interinstitucional de Pós-Graduação em Ciências Fisiológicas - PIPGCF, Câmpus São Carlos, 06/09/2019)Breast cancer is the second most common type in the world and can be considered a disease with good prognosis if diagnosed early and treated timely. The treatment of breast cancer aims to increase survival and improve the ...