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Participação de pequenos grupos neurais seletivamente ativados do córtex pré-límbico na reinstalação da autoadministração de etanol induzida pelo contexto
(Universidade Federal de São Carlos, 2017-05-12)
Context-induced reinstatement of drug seeking is an animal model for assessing the neural mechanisms underlying context-induced drug relapse, a major factor in human drug addiction. Neural activity in prelimbic cortex has ...
Função colinérgica do núcleo do trato solitário comissural nas respostas cardiorrespiratórias à hipóxia e hipercapnia
(Universidade Federal de São Carlos, 2017-08-11)
The nucleus of the solitary tract (NTS) is the primary site of visceral afferents, such as baroreceptors and arterial chemoreceptors. Recent data from our laboratory have shown that the microinjection of acetylcholine (ACh) ...
A região A5 e o controle respiratório durante o desenvolvimento
(Universidade Federal de São Carlos, 2017-04-13)
The noradrenergic group A5 is located in the ventrolateral pons and contributes to the maturation of the respiratory system before birth in rats. These neurons are connected to the neural network responsible for respiratory ...
Efeito do bloqueio dos receptores mineralocorticoides da região infra-límbica do córtex pré-frontal medial sobre a tolerância aos efeitos do midazolam em camundongos submetidos ao protocolo de teste e reteste no labirinto em cruz elevado
(Universidade Federal de São Carlos, 2017-05-25)
Several studies have shown that the previous experience (trial 1) to the elevated plus-maze
(EPM) increases the avoidance of the open arms and impairs the anxiolytic-like effect of
midazolam (MDZ), a benzodiazepine-GABAA ...
Efeito do treinamento intervalado de alta intensidade na composição corporal, na regulação do processo inflamatório e do metabolismo de ratos Wistar alimentados com dieta hiperlipídica
(Universidade Federal de São Carlos, 2017-09-04)
This study aims to analyze the behavior of Omentin and Vaspin in relation to a high intensity interval training protocol (HIIT) in rats fed a hyperlipidic diet. To this end, male Wistar rats, divided into 4 groups, received ...
Envolvimento de receptores muscarínicos centrais no controle da ingestão de sódio
(Universidade Federal de São Carlos, 2017-07-10)
Water and sodium intake are fundamental behaviors for body fluid homeostasis. These behaviors are controlled by a neural circuitry involving facilitatory and inhibitory mechanisms, which are modulated by signals activated ...
Efeitos de um derivado semissintético do [6]-gingerol na autofagia e apoptose em células de câncer de mama
(Universidade Federal de São Carlos, 2017-05-09)
In this work, we describe a semisynthetic derivative of [6]-gingerol called SSi6, which induces cytotoxic effects on the MDA-MB-231 breast tumor, showing a greater selectivity for these cells when compared to the non-tumor ...
Treinamento resistido e restrição calórica : fatores de proteção cardiovascular em ratas ovariectomizadas
(Universidade Federal de São Carlos, 2017-06-29)
Introduction: Hypertension is an important risk factor for menopausal cardiovascular disease. Resistance training (RT) when associated with the caloric restriction diet (CR) has been shown to have important effects on blood ...
Avaliação dos efeitos antitumorais do complexo de rutênio [Ru(GA)(dppe)2]PF6 em células não-tumorais e tumorais de mama cultivadas in vitro
(Universidade Federal de São Carlos, 2017-05-12)
Cancers have become an increasingly relevant problem of public health in the last decades. Within neoplastic diseases, breast cancer is one of the most incidental in female population and related to a high mortality rate. ...
Papel do cortex pré-frontal medial no comportamento defensivo de camundongos : avaliação farmacológica da lateralização funcional
(Universidade Federal de São Carlos, 2017-04-13)
Stressful situations are risk factors to the development of neuropsychiatric diseases, as anxiety disorders. However, not everyone who experiences stressful events develops stress-related illness. That is due to the existence ...