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O bloqueio dos receptores NMDA ou CRF1 no núcleo intersticial da estria terminal impede a ansiogênese induzida pela ativação nitrérgica do córtex pré-frontal medial e derrota social em camundongos
(Universidade Federal de São Carlos, 2019-09-20)
Nitric oxide (NO) release in the right medial prefrontal cortex (RmPFC) produces anxiogenesis. In the bed nucleus of the stria terminalis (BNST), a region that receives neuronal projections from the mPFC, NO also provokes ...
Efeitos de complexos metálicos de cobre no câncer de mama triplo negativo
(Universidade Federal de São Carlos, 2019-09-06)
Breast cancer is the second most common type in the world and can be considered a disease with good prognosis if diagnosed early and treated timely. The treatment of breast cancer aims to increase survival and improve the ...
Envolvimento de neurotransmissões angiotensinérgicas no núcleo medial da amídala nas respostas cardiovasculares e ansiogênica ao estresse de restrição em ratos
(Universidade Federal de São Carlos, 2020-09-04)
Limbic structures participate in the control of physiological responses related to stress, and the medial amigdaloid nucleus (MeA) has been demonstrated as an area of the central nervous system involved in the control these ...
Controle das respostas cardiovasculares ao estresse pela neurotransmissão endocanabinóide no núcleo leito da estria terminal em ratos: interação com a via de sinalização receptor NMDA/nNOS/GCs/proteína quinase G e envolvimento do hipotálamo lateral
(Universidade Federal de São Carlos, 2020-09-23)
The bed nucleus of the stria terminalis (BNST) is a structure located in the rostral forebrain, which has been implicated in autonomic, neuroendocrine and behavioral responses during aversive situations. A recent study ...
Lidando com o inimigo: caracterização comportamental, molecular e cardiovascular de roedores resilientes e susceptíveis ao estresse de derrota social
(Universidade Federal de São Carlos, 2021-03-10)
Despite the well-known correlation between prolonged stress and the development of diseases, not every individual exposed to stressful situations develops stress-related disorders. This individual difference could be related ...
Os sistemas serotonérgico, gabaérgico e endocanabinoide da amígdala medeiam a empatia relacionada à nocicepção em camundongos
(Universidade Federal de São Carlos, 2020-08-28)
Evidence shows a reciprocal relationship between chronic pain and emotional disorders, exacerbating the other's experience. The affective-emotional component of pain can be activated not only in those who feel the pain but ...