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Efeito de um complexo de rutênio em células de câncer de mama em diferentes modelos 2D e 3D in vitro e in vivo
(Universidade Federal de São Carlos, 2019-10-18)
Cancer is among the leading causes of morbidity and mortality in the world. Specifically, breast cancer is an extremely heterogeneous disease, being composed of different subtypes and this heterogeneity makes treatment ...
Envolvimento dos receptores centrais angiotensinérgicos e mineralocorticóides no aumento do apetite ao sódio induzido por privação hídrica em ratos com hipertensão renovascular
(Universidade Federal de São Carlos, 2020-04-27)
Sodium appetite in normotensive rats submitted to water deprivation (WD) for 24 h followed by 2 h with access to water only (partial rehydration–PR) depends on the activation of the renin-angiotensin system (RAS). ...
Efeito do treinamento aeróbio de natação no conteúdo de GLUT4 e FAT CD36 e metabolismo energético de ratas ovariectomizadas
(Universidade Federal de São Carlos, 2020-03-02)
The end of ovarian secretion of estrogens is associated with imbalance of energy substrates, raising the risk of metabolic diseases. Physical training (PT) corresponds to non-pharmacological treatment in this context, ...
Estudo dos efeitos do bloqueio da integrina αvβ3 por uma desintegrina RGD recombinante na cicatrização de hérnia incisional em ratos
(Universidade Federal de São Carlos, 2014-06-27)
Introduction: Incisional hernia (IH) is considered a connective tissue disease characterized by defective wound healing process, and it is found in high incidence after abdominal surgeries. Previous studies have shown that ...
Efeitos da deleção de REST do músculo esquelético sobre a composição corporal e função muscular de camundongos c57bl/6
(Universidade Federal de São Carlos, 2018-10-26)
In order to elucidate the role of skeletal muscle REST (RE1 Silencing Transcription Factor) protein on body composition and muscle functionality, we aimed at evaluating the effects of the specific deletion of REST from ...
Efeito do treinamento de força realizado com duração de repetição controlada e auto-selecionada na força e massa muscular de homens jovens
(Universidade Federal de São Carlos, 2018-09-25)
The aim of the study was to compare the effect of RD SELF, with and without total training volume equalized with RD CON, on muscle strength and hypertrophy. Twenty healthy untrained university students were recruited for ...
O sistema renina-angiotensina e a palatabilidade do sabor salgado em ratos com apetite ao sódio
(Universidade Federal de São Carlos, 2020-05-08)
The renin-angiotensin system (RAS) belongs to mechanisms that control the search and ingestion of hypertonic NaCl in rats with sodium apetite. Here we investigate whether the antagonism of RAS affects hedonic and aversive ...
Efeitos do treinamento aeróbio no conteúdo da proteína utrofina e nas propriedades contráteis do músculo tibial anterior de camundongos mdx: modelo experimental da Distrofia Muscular de Duchenne
(Universidade Federal de São Carlos, 2020-07-31)
Introduction: Duchenne muscular dystrophy (DMD) is the most common and severe muscular dystrophy caused by the absence of the dystrophin protein that determines, progressive loss of muscle fibers and muscle weakness. It ...
Alterações cardiovasculares e hidro-eletrolíticas induzidas por dieta hiperlipídica
(Universidade Federal de São Carlos, 2019-02-22)
Obesity has been pointed out as a worldwide epidemic. Data from the literature show that obesity can promote cardiovascular diseases such as hypertension, and the increased activity of the renin-angiotensin system (RAS) ...
Efeitos do treinamento físico na adiposidade visceral, tecido adiposo marrom e parâmetros metabólicos de ratos Wistar alimentados com dieta hiperlipídica
(Universidade Federal de São Carlos, 2020-07-15)
Obesity is a multifactorial disease that produces various metabolic disorders through the local and systemic inflammatory response occasioned by the pathological remodeling of visceral white adipose tissue (WAT). Furthermore, ...