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Atividade metaloproteinases e propriedades físicas, químicas e biomecânicas de ossos de ratos tratados com cloreto de mercúrio
(Universidade Federal de São Carlos, 2011-09-15)
There are few data about the mercury influence on bone metabolism them it is important to investigate the bone parameters that can be affected by it. The aim of this study was to evaluate the biometric, physical, biomechanical ...
Estudo dos efeitos do bloqueio da integrina αvβ3 por uma desintegrina RGD recombinante na cicatrização de hérnia incisional em ratos
(Universidade Federal de São Carlos, 2014-06-27)
Introduction: Incisional hernia (IH) is considered a connective tissue disease characterized by defective wound healing process, and it is found in high incidence after abdominal surgeries. Previous studies have shown that ...
Estudo da participação da neurotransmissão CRFérgica do núcleo leito da estria terminal (NLET) no controle da função cardiovascular em ratos: envolvimento nas alterações cardiovasculares induzidas pelo estresse crônico variado?
(Universidade Federal de São Carlos, 2020-03-06)
The aim of the present study was to investigate the role of CRFergic neurotransmission into bed nucleus of stria terminalis (BNST) on cardiovascular function. We observed that bilateral microinjection of the selective CRF1 ...
Efeito de um complexo de rutênio em células de câncer de mama em diferentes modelos 2D e 3D in vitro e in vivo
(Universidade Federal de São Carlos, 2019-10-18)
Cancer is among the leading causes of morbidity and mortality in the world. Specifically, breast cancer is an extremely heterogeneous disease, being composed of different subtypes and this heterogeneity makes treatment ...
O papel do circuito hipocampo ventral - córtex pré-frontal medial na memória de reconhecimento e espacial (recente e remota) de ratos wistar
(Universidade Federal de São Carlos, 2020-03-30)
The medial prefrontal cortex (mPFC) and the hippocampus (HPC) have well-established roles in processing memories. Ventral portion of the HPC (vHPC) and mPFC have reciprocal connections and seems to be involved with processing ...
Efeitos da deleção de REST do músculo esquelético sobre a composição corporal e função muscular de camundongos c57bl/6
(Universidade Federal de São Carlos, 2018-10-26)
In order to elucidate the role of skeletal muscle REST (RE1 Silencing Transcription Factor) protein on body composition and muscle functionality, we aimed at evaluating the effects of the specific deletion of REST from ...
Efeitos do extrato de Lycium barbarum L. e do laser vermelho na prevenção e tratamento do fotoenvelhecimento cutâneo em camundongos hairless
(Universidade Federal de São Carlos, 2018-12-17)
In the aging process an organic functional decrease occurs. Ultraviolet Radiation (UVR), from the sun, is its main etiological agent. Cellular and structural changes arise as a consequence of the association between UVR ...
Transplante de células tronco mesenquimais melhora a função motora e modula marcadores de atrofia muscular em ratos diabéticos
(Universidade Federal de São Carlos, 2017-10-10)
Hyperglycemia causes sensorimotor disorder and muscle atrophy for which there is no satisfactory therapy. Stem cell therapy is an attractive strategy for diabetic complications due to its capacity to differentiate into ...
ADAM10 como biomarcadora de Transtorno Neurocognitivo Leve
(Universidade Federal de São Carlos, 2020-09-28)
Mild cognitive impairment (MCI), in the absence of dementia, and associated with physical frailty gave rise to the new concept called cognitive frailty. This new concept has also been considered as a subtype of frailty. ...
Envolvimento de neurotransmissões angiotensinérgicas no núcleo medial da amídala nas respostas cardiovasculares e ansiogênica ao estresse de restrição em ratos
(Universidade Federal de São Carlos, 2020-09-04)
Limbic structures participate in the control of physiological responses related to stress, and the medial amigdaloid nucleus (MeA) has been demonstrated as an area of the central nervous system involved in the control these ...