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Avaliação da atividade antitumoral in vitro e in vivo de novos complexos de rutênio contendo ácido salicílico e derivados
(Universidade Federal de São Carlos, 2021-04-30)
Cancer is a term used for diseases in which abnormal cells divide uncontrolled, spread, and invade other tissues through the blood and lymphatic systems. Breast cancer is one of the most common and with higher mortality ...
Lateralização funcional do córtex pré-frontal medial na ansiedade em camundongos: avaliações molecular e psicofarmacológica
(Universidade Federal de São Carlos, 2021-08-05)
The left and right medial prefrontal cortex (L & RmPFC) process emotional responses induced by stress-related stimuli, and LmPFC and RmPFC inhibition elicit anxiogenesis and anxiolysis, respectively. Here we sought to ...
Ajustes cardiovasculares em modelo experimental descerebrado, cascavel sul americana (Crotalus durissus)
(Universidade Federal de São Carlos, 2021-12-03)
The reptile class has considerable importance among vertebrates for investigations about the evolution of modulatory mechanisms in the cardiovascular system. Some cardiovascular studies have been performed with in situ ...
Estudo da participação da neurotransmissão CRFérgica do núcleo leito da estria terminal (NLET) no controle da função cardiovascular em ratos: envolvimento nas alterações cardiovasculares induzidas pelo estresse crônico variado?
(Universidade Federal de São Carlos, 2020-03-06)
The aim of the present study was to investigate the role of CRFergic neurotransmission into bed nucleus of stria terminalis (BNST) on cardiovascular function. We observed that bilateral microinjection of the selective CRF1 ...
ADAM10 como biomarcadora de Transtorno Neurocognitivo Leve
(Universidade Federal de São Carlos, 2020-09-28)
Mild cognitive impairment (MCI), in the absence of dementia, and associated with physical frailty gave rise to the new concept called cognitive frailty. This new concept has also been considered as a subtype of frailty. ...
Envolvimento de neurotransmissões angiotensinérgicas no núcleo medial da amídala nas respostas cardiovasculares e ansiogênica ao estresse de restrição em ratos
(Universidade Federal de São Carlos, 2020-09-04)
Limbic structures participate in the control of physiological responses related to stress, and the medial amigdaloid nucleus (MeA) has been demonstrated as an area of the central nervous system involved in the control these ...
Influência da obesidade sobre as morfologias de onda da pressão intracraniana e cerebral: um estudo prospectivo
(Universidade Federal de São Carlos, 2021-05-13)
Introduction: Obesity is a low-grade inflammatory disease, which can lead to the development of other pathologies, such as diabetes mellitus, dyslipidemias and arterial hypertension (AH). Compare the relationship between ...
Modulação de Irisina, composição corporal, e parâmetros metabólicos em ratos Wistar obesos exógenos frente ao protocolo de treinamento aeróbico e/ou intervenção dietética
(Universidade Federal de São Carlos, 2021-05-17)
Obesity is a disease characterized by the expansion of adipose tissue, which promotes the secretion of factors that lead to comorbidities, such as diabetes and cardiovascular disease. In this sense, dietary intervention ...
Controle das respostas cardiovasculares ao estresse pela neurotransmissão endocanabinóide no núcleo leito da estria terminal em ratos: interação com a via de sinalização receptor NMDA/nNOS/GCs/proteína quinase G e envolvimento do hipotálamo lateral
(Universidade Federal de São Carlos, 2020-09-23)
The bed nucleus of the stria terminalis (BNST) is a structure located in the rostral forebrain, which has been implicated in autonomic, neuroendocrine and behavioral responses during aversive situations. A recent study ...
Lidando com o inimigo: caracterização comportamental, molecular e cardiovascular de roedores resilientes e susceptíveis ao estresse de derrota social
(Universidade Federal de São Carlos, 2021-03-10)
Despite the well-known correlation between prolonged stress and the development of diseases, not every individual exposed to stressful situations develops stress-related disorders. This individual difference could be related ...