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Avaliação da atividade antitumoral in vitro e in vivo de novos complexos de rutênio contendo ácido salicílico e derivados
(Universidade Federal de São Carlos, 2021-04-30)
Cancer is a term used for diseases in which abnormal cells divide uncontrolled, spread, and invade other tissues through the blood and lymphatic systems. Breast cancer is one of the most common and with higher mortality ...
Estudo da participação da neurotransmissão CRFérgica do núcleo leito da estria terminal (NLET) no controle da função cardiovascular em ratos: envolvimento nas alterações cardiovasculares induzidas pelo estresse crônico variado?
(Universidade Federal de São Carlos, 2020-03-06)
The aim of the present study was to investigate the role of CRFergic neurotransmission into bed nucleus of stria terminalis (BNST) on cardiovascular function. We observed that bilateral microinjection of the selective CRF1 ...
O papel do circuito hipocampo ventral - córtex pré-frontal medial na memória de reconhecimento e espacial (recente e remota) de ratos wistar
(Universidade Federal de São Carlos, 2020-03-30)
The medial prefrontal cortex (mPFC) and the hippocampus (HPC) have well-established roles in processing memories. Ventral portion of the HPC (vHPC) and mPFC have reciprocal connections and seems to be involved with processing ...
ADAM10 como biomarcadora de Transtorno Neurocognitivo Leve
(Universidade Federal de São Carlos, 2020-09-28)
Mild cognitive impairment (MCI), in the absence of dementia, and associated with physical frailty gave rise to the new concept called cognitive frailty. This new concept has also been considered as a subtype of frailty. ...
Envolvimento de neurotransmissões angiotensinérgicas no núcleo medial da amídala nas respostas cardiovasculares e ansiogênica ao estresse de restrição em ratos
(Universidade Federal de São Carlos, 2020-09-04)
Limbic structures participate in the control of physiological responses related to stress, and the medial amigdaloid nucleus (MeA) has been demonstrated as an area of the central nervous system involved in the control these ...
Controle das respostas cardiovasculares ao estresse pela neurotransmissão endocanabinóide no núcleo leito da estria terminal em ratos: interação com a via de sinalização receptor NMDA/nNOS/GCs/proteína quinase G e envolvimento do hipotálamo lateral
(Universidade Federal de São Carlos, 2020-09-23)
The bed nucleus of the stria terminalis (BNST) is a structure located in the rostral forebrain, which has been implicated in autonomic, neuroendocrine and behavioral responses during aversive situations. A recent study ...
A influência do treinamento físico em ratos espontaneamente hipertensos tratados com dexametasona: contribuição dos microRNAs
(Universidade Federal de São Carlos, 2020-09-02)
Hypertension (HT) is a multifactorial disease characterized by elevated and sustained blood pressure (BP), which can be primary or secondary. Dexamethasone (DEX) is a synthetic glucocorticoid and its chronic use causes ...
Participação do óxido nítrico no efeito hipotensivo e vasodilatador induzido pela fotobiomodulação utilizando laser de 660 nm
(Universidade Federal de São Carlos, 2021-03-24)
Introduction: Photobiomodulation (PBM) is a non-invasive therapeutic modality used to treat several pathologies. Studies indicate that nitric oxide (NO) can be released from endogenous “stocks” by photolysis, favoring the ...
Lidando com o inimigo: caracterização comportamental, molecular e cardiovascular de roedores resilientes e susceptíveis ao estresse de derrota social
(Universidade Federal de São Carlos, 2021-03-10)
Despite the well-known correlation between prolonged stress and the development of diseases, not every individual exposed to stressful situations develops stress-related disorders. This individual difference could be related ...
Manipulações das variáveis do treinamento de força ou fatores biológicos intrínsecos: o que determina a magnitude da hipertrofia muscular?
(Universidade Federal de São Carlos, 2022-03-29)
We aimed to investigate whether muscle fiber cross-sectional area (fCSA) and associated molecular processes could be differently affected at the group and individual level by manipulating resistance training (RT) variables. ...