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Sensibilização comportamental à cocaína e neuroadaptações na via mesocorticolímbica : interação com ontogênese, estresse e ambiente
(Universidade Federal de São Carlos, 2009-03-05)
We investigated the interaction between ontogeny, stress and
environment where the drug is administered on the behavioral sensitization to cocaine and related neuroadaptations. This study was divided in two parts. In the ...
Lateralização funcional do córtex pré-frontal medial na ansiedade em camundongos: avaliações molecular e psicofarmacológica
(Universidade Federal de São Carlos, 2021-08-05)
The left and right medial prefrontal cortex (L & RmPFC) process emotional responses induced by stress-related stimuli, and LmPFC and RmPFC inhibition elicit anxiogenesis and anxiolysis, respectively. Here we sought to ...
Investigação do tratamento com N-acetilcisteína nos comportamentos relacionados à ansiedade durante a síndrome de abstinência do etanol e na resposta cardiovascular induzida pelo estresse em ratos
(Universidade Federal de São Carlos, 2019-02-08)
N-acetylcysteine (NAC) for decades, has been shown to have beneficial effects for the treatment of some diseases. Recently, based on central glutamatergic neurotransmission, psychiatric disorders and the stress response ...
Mecanismos comportamentais e moleculares envolvidos na interação entre as substâncias de abuso e os fatores de risco para o desenvolvimento da dependência
(Universidade Federal de São Carlos, 2013-03-08)
Tobacco and ethanol are the most used drugs in the world and often co-abused. An important issue in the field of drug abuse research is the characterization of risk factors related to increased vulnerability to drug ...
Estudo da participação da neurotransmissão CRFérgica do núcleo leito da estria terminal (NLET) no controle da função cardiovascular em ratos: envolvimento nas alterações cardiovasculares induzidas pelo estresse crônico variado?
(Universidade Federal de São Carlos, 2020-03-06)
The aim of the present study was to investigate the role of CRFergic neurotransmission into bed nucleus of stria terminalis (BNST) on cardiovascular function. We observed that bilateral microinjection of the selective CRF1 ...
Envolvimento de neurotransmissões angiotensinérgicas no núcleo medial da amídala nas respostas cardiovasculares e ansiogênica ao estresse de restrição em ratos
(Universidade Federal de São Carlos, 2020-09-04)
Limbic structures participate in the control of physiological responses related to stress, and the medial amigdaloid nucleus (MeA) has been demonstrated as an area of the central nervous system involved in the control these ...