Browsing Biotecnologia - Biotec by Subject "Mitocôndria"
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Caracterização das alterações transcricionais e morfológica da mitocôndria da prole de fêmeas obesas com deficiência da mitofusina 2 no oócito
(Universidade Federal de São Carlos, UFSCar, , Câmpus São Carlos, 26/01/2024)Heart disease is one of the main causes of death worldwide and research has shown an intrinsic relationship between cardiac effects in offspring and maternal obesity. In addition, there is increasing evidence of the possible ... -
Efeito do nocaute fígado-específico da Mitofusina 2 sobre o acúmulo de DNA mitocondrial NZB/BINJ em camundongos
(Universidade Federal de São Carlos, UFSCar, , Câmpus São Carlos, 19/11/2021)The mammalian mitochondrial DNA (mtDNA) shows a high mutation frequency, which can lead to severe diseases in humans. However, disease development relies on the mutation load, which is tissue specific. This is explained ...