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Caracterização de células estromais mesenquimais multipotentes cultivadas na presença de uma molécula moduladora da expressão de ciclo-oxigenase-2
(Universidade Federal de São Carlos, 2019-03-28)
Mesenchymal stromal cells (MSC) are stem cells used in therapeutic applications due to their regenerative and immunomodulatory potential. These cells exhibit paracrine activity, which releases soluble factors that allow ...
Aplicações biotecnológicas da taumatina
(Universidade Federal de São Carlos, 2023-04-03)
Thaumatin is a protein present in the leaves of the plant Thaumatococcus daniellii, native to West Africa. This protein is known for its intensely sweet taste and for being about 2000 times sweeter than sugar. For this ...
Longevidade diferencial de fêmeas adultas de Apis mellifera
(Universidade Federal de São Carlos, 2023-04-05)
Adult females of Apis mellifera bee species exhibit variation in their longevity, with queens and laying workers (such as anarchists, pseudo queens, and queenless/orphaned workers) living longer than non-laying workers, ...
DNA barcoding de mamíferos atropelados da amazônia ocidental: um estudo em cutia, cutiara e paca
(Universidade Federal de São Carlos, 2023-08-29)
DNA barcoding is a relatively recent method that allows for the molecular identification of a species from a molecular marker, based on the premise that each species has a unique sequence, which is a barcode sequence. For ...
Inibição da integrina αvβ3 em cultura celular 3D de células tumorais e endoteliais em ambiente hipóxico utilizando a desintegrina recombinante DisBa-01
(Universidade Federal de São Carlos, 2022-11-11)
Breast cancer has a high global incidence, it was the most fatal type of cancer in 2020, When 66,280 new cases were estimated just in Brazil. The main problems associated with tumors are related to their metastatic behavior, ...
Análise citogenética de espécies e híbridos interespecíficos de Paspalum L. (Poaceae)
(Universidade Federal de São Carlos, 2023-01-25)
The genus Paspalum L. (Poaceae) comprises about 350 species, many of which are characterized by high forage potential. The genus presents predominantly polyploid apomictic and diploid sexual species. For breeding programs, ...
Identificação e expressão recombinante de um novo peptídeo de potencial antimicrobiano derivado da proteína de reconhecimento de Peptidoglicanos 3 humana
(Universidade Federal de São Carlos, 2024-02-20)
During the 21st century, bacterial resistance to drugs has reached dangerous levels, necessitating the development of new therapeutic strategies to combat these pathogens. Among them, antimicrobial peptides (AMPs) emerge ...
Efeitos da injeção intra-articular de plasma rico em plaquetas versus ácido hialurônico no processo inflamatório e características histopatológicas da cartilagem e sinóvia em animais com osteoartrite: uma revisão sistemática
(Universidade Federal de São Carlos, 2023-03-27)
Osteoarthritis (OA) is a disease characterized by the wearing down of joint cartilage and changes in bone structures, causing pain and compromising patients' quality of life. One of the treatment options is intra-articular ...
Proteínas modificadoras de sabor: produção recombinante e suas aplicações biotecnológicas
(Universidade Federal de São Carlos, 2023-03-22)
A class of sweet-tasting proteins from tropical forest plant fruits has been studied for their sweetening potential and also for their taste-modifier activity. The taste-modifier proteins have the ability to change bitter ...
Construção de vetor plasmidial para deleção gênica da ORF XAC3162 de Xanthomonas citri subsp.citri
(Universidade Federal de São Carlos, 2023-03-31)
Citrus canker is a bacterial disease caused by Xanthomonas citri (XAC), which affects all citrus species and causes damage to fruit quality and productivity. In 2022, in Brazil, the world´s largest producer of oranges, the ...