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Inibição da integrina αvβ3 em cultura celular 3D de células tumorais e endoteliais em ambiente hipóxico utilizando a desintegrina recombinante DisBa-01
(Universidade Federal de São Carlos, 2022-11-11)
Breast cancer has a high global incidence, it was the most fatal type of cancer in 2020, When 66,280 new cases were estimated just in Brazil. The main problems associated with tumors are related to their metastatic behavior, ...
Avaliação do domínio ATPásico da proteína não estrutural 3 (NS3) do vírus da Zika e investigação de derivados de hidantoínas e oxadiazol como agentes antivirais baseados na estrutura da proteína
(Universidade Federal de São Carlos, 2022-09-20)
One of the great challenges in the field of public health in Brazil has been related to the existence of flaviviruses that cause diseases with high rates of contamination, such as to Dengue, Zika and Chikungunya. The ...
Avaliação de vetores de expressão para Xantomonas ssp. aplicados à produção de goma xantana
(Universidade Federal de São Carlos, 2022-02-24)
Xanthomonas sp. are proteobacteria widely known for its pathogenic association with varied species of plants, such as Xanthomonas campestris, which causes black rot that affects crucifers. Its pathogenicity is partially ...
Análise do efeito do agente crioprotetor dimetilsulfóxido (DMSO) visando melhorar a criopreservação de microalgas
(Universidade Federal de São Carlos, 2022-04-29)
Cryopreservation is a technique that adds ease of maintenance of collections and genetic preservation of strains, but it has a high failure rate and problems in the rehabilitation of strains, using cryopreservers (CPA) ...
Caracterização da cianobactéria Rhabdoderma lineare: uma abordagem fisiológica, bioquímica e metabólica
(Universidade Federal de São Carlos, 2022-09-12)
Cyanobacteria are a group of single-celled, prokaryote and photosynthetic organisms. It has an enormous morphological, physiological and metabolic diversity and this allows the application of these organisms in several ...
Imunoensaio de fluxo lateral para diagnóstico de tuberculose
(Universidade Federal de São Carlos, 2022-11-09)
Tuberculosis is the leading cause of death among infectious diseases, according to the World Health Organization, and represents a major public health problem. About 1.4 million people died from tuberculosis worldwide in ...
Biossensor eletroquímico para detecção de vesículas extracelulares pequenas provenientes de câncer de mama
(Universidade Federal de São Carlos, 2022-02-04)
Cancer is a group of diseases characterized by the disordered proliferation of cells, which can invade other organs and tissues. Breast cancer (BC) is the most common disease in women worldwide, with more than 2 million ...
Triagens de alta performance para a descoberta de agentes anti-Zika vírus
(Universidade Federal de São Carlos, 2022-04-13)
The Zika virus (ZIKV) is an mosquito-borne transmitted by the bite of the Aedes aegypti mosquito, which became a public health problem during the 2015/2016 outbreak in the Americas and mainly in Brazil, where it was related ...
Genossensor eletroquímico contendo nanopartículas de ouro Para detecção sensível de sars-cov-2
(Universidade Federal de São Carlos, 2022-04-18)
Since the emergence of the new coronavirus (SARS-CoV-2), more than 495 million people have been affected by this disease, leading to an estimated 6.17 million deaths. In this context, the World Health Organization (WHO) ...
COVID-19: da origem aos aspectos imunológicos baseados em ontologia genética
(Universidade Federal de São Carlos, 2022-01-12)
Coronaviruses are a group of viruses that includes SARS-CoV-2 (severe acute respiratory syndrome coronavirus 2), which causes COVID-19 (coronavirus disease 2019), a disease that had its first outbreak in China in December ...