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Eccentric left ventricular hypertrophy, left and right cardiac function in Chronic Heart Failure with or without coexisting COPD: impact on exercise performance

dc.contributor.authorSantos, Polliana Batista dos
dc.contributor.authorSimões, Rodrigo Polaquini
dc.contributor.authorGoulart, Cássia da Luz
dc.contributor.authorRoscani, Meliza Goi
dc.contributor.authorMarinho, Renan Shida
dc.contributor.authorCamargo, Patricia Faria
dc.contributor.authorArbex, Renata F.
dc.contributor.authorCasale, Guilherme
dc.contributor.authorOliveira, Cláudio Ricardo de
dc.contributor.authorMendes, Renata Gonçalves
dc.contributor.authorArena, Ross
dc.contributor.authorSilva, Audrey Borghi
dc.date.accessioned2022-02-08T10:27:45Z
dc.date.available2022-02-08T10:27:45Z
dc.date.issued2021-02-03
dc.identifierhttps://doi.org/10.2147/copd.s285812por
dc.identifier.citationSANTOS, Polliana Batista dos; SIMÕES, Rodrigo Polaquini; GOULART, Cássia da Luz; ROSCANI, Meliza Goi; MARINHO, Renan Shida; CAMARGO, Patricia Faria; ARBEX, Renata F.; CASALE, Guilherme; OLIVEIRA, Cláudio Ricardo de; MENDES, Renata Gonçalves; ARENA, Ross; SILVA, Audrey Borghi. Eccentric left ventricular hypertrophy, left and right cardiac function in Chronic Heart Failure with or without coexisting COPD: impact on exercise performance. Repositório Institucional da UFSCar, 2021. Dataset. Disponível em: https://repositorio.ufscar.br/handle/ufscar/15554.*
dc.identifier.urihttps://repositorio.ufscar.br/handle/ufscar/15554
dc.descriptionAbstract Aim: Our aim was to assess: 1) the impact of the eccentric left ventricular hypertrophy (ELVH) on exercise performance in patients diagnosed with chronic heart failure (CHF) alone and in patients with co-existing CHF and chronic obstructive pulmonary disease (COPD) and 2) the relationship between left and right cardiac function measurements obtained by doppler echocardiography, clinical characteristics and primary measures of cardiorespiratory fitness. Methods: The current study included 46 patients (CHF:23 and CHF+COPD:23) that performed advanced pulmonary function tests, echocardiography and symptom-limited, incremental cardiopulmonary exercise testing (CPET) on a cycle ergometer. Results: Patients with CHF+COPD demonstrated a lower work rate, peak oxygen uptake (VO2), oxygen pulse, rate pressure product (RPP), circulatory power (CP) and ventilatory power (VP) compared to those only diagnosed with CHF. In addition, significant correlations were observed between VP and relative wall thickness (r: 0.45 p: 0.03),VE/VCO2 intercept and Mitral E/e' ratio (r: 0.70 p: 0.003) in the CHF group. Significant correlations were found between indexed left ventricle mass and RPP (r: -0.47; p: 0.02) and relative VO2 and right ventricle diameter (r: -0.62; p: 0.001) in the CHF+COPD group. Conclusion: Compared to a diagnosis of CHF alone, a combined diagnosis of CHF+COPD induced further impairments in cardiorespiratory fitness. Moreover, echocardiographic measures of cardiac function are related to cardiopulmonary exercise performance and therefore appear to be an important therapeutic target when attempting to improve exercise performance and functional capacity.eng
dc.description.sponsorshipCoordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES)por
dc.description.sponsorshipFundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)por
dc.language.isoengeng
dc.publisherUniversidade Federal de São Carlospor
dc.relation.urihttps://repositorio.ufscar.br/handle/ufscar/15361
dc.relation.urihttps://www.dovepress.com/eccentric-left-ventricular-hypertrophy-and-left-and-right-cardiac-func-peer-reviewed-fulltext-article-COPD
dc.rightsAttribution-NonCommercial-NoDerivs 3.0 Brazil*
dc.rights.urihttp://creativecommons.org/licenses/by-nc-nd/3.0/br/*
dc.subjectCardiopulmonary exercise testingeng
dc.subjectChronic obstructive pulmonary diseaseeng
dc.subjectEccentric hypertrophyeng
dc.subjectEchocardiographyeng
dc.subjectHeart failureeng
dc.subjectVentricular dysfunctioneng
dc.titleEccentric left ventricular hypertrophy, left and right cardiac function in Chronic Heart Failure with or without coexisting COPD: impact on exercise performanceeng
dc.typeDatasetpor
dc.publisher.initialsUFSCarpor
dc.publisher.programPrograma de Pós-Graduação em Fisioterapia - PPGFtpor
dc.subject.cnpqCIENCIAS DA SAUDE::FISIOTERAPIA E TERAPIA OCUPACIONALpor
dc.description.sponsorshipId2015/26501-1por
dc.description.sponsorshipId2018/03314-0por
dc.description.sponsorshipIdCódigo de Financiamento 001por
dc.publisher.addressCâmpus São Carlospor
dc.contributor.authorlatteshttp://lattes.cnpq.br/9224940191005426por
dc.contributor.authorlatteshttp://lattes.cnpq.br/2731345085062145por
dc.contributor.authorlatteshttp://lattes.cnpq.br/9790656360225486por
dc.contributor.authorlatteshttp://lattes.cnpq.br/1298051150234135por
dc.contributor.authorlatteshttp://lattes.cnpq.br/0976845548972921por
dc.contributor.authorlatteshttp://lattes.cnpq.br/8975177658472167por
dc.contributor.authorlatteshttp://lattes.cnpq.br/3965315647105124por
dc.contributor.authorlatteshttp://lattes.cnpq.br/2378989092427082por
dc.contributor.authorlatteshttp://lattes.cnpq.br/5091705745613726por
dc.contributor.authorlatteshttp://lattes.cnpq.br/9634590922242052por
dc.contributor.authorlatteshttp://lattes.cnpq.br/4855616925791895por
dc.publisher.departmentDepartamento de Fisioterapia - DFisiopor


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