dc.contributor.author | Castello-Simões, Viviane | |
dc.contributor.author | Kabbach, Erika Zavaglia | |
dc.contributor.author | Schafauser, Nathany Souza | |
dc.contributor.author | Camargo, Patrícia Faria | |
dc.contributor.author | Simões, Rodrigo Polaquini | |
dc.contributor.author | Heubel, Alessandro Domingues | |
dc.contributor.author | Alqahtani, Jaber Saud | |
dc.contributor.author | Pereira, Mariana Brasil da Cunha Martino | |
dc.contributor.author | Sgarbosa, Nicole Marques | |
dc.contributor.author | Silva, Audrey Borghi | |
dc.contributor.author | Mendes, Renata Gonçalves | |
dc.date.accessioned | 2022-02-09T10:31:18Z | |
dc.date.available | 2022-02-09T10:31:18Z | |
dc.date.issued | 2021-06-19 | |
dc.identifier | https://doi.org/10.1016/j.rmed.2021.106511 | por |
dc.identifier.citation | CASTELLO-SIMÕES, Viviane; KABBACH, Erika Zavaglia; SCHAFAUSER, Nathany Souza; CAMARGO, Patrícia Faria; SIMÕES, Rodrigo Polaquini; HEUBEL, Alessandro Domingues; ALQAHTANI, Jaber Saud; PEREIRA, Mariana Brasil da Cunha Martino; SGARBOSA, Nicole Marques; SILVA, Audrey Borghi; MENDES, Renata Gonçalves. Brain-heart autonomic axis across different clinical status and severity of chronic obstructive pulmonary disease. Repositório Institucional da UFSCar, 2021. Dataset. Disponível em: https://repositorio.ufscar.br/handle/ufscar/15572. | * |
dc.identifier.uri | https://repositorio.ufscar.br/handle/ufscar/15572 | |
dc.description | Purpose: Impairment of cardiac autonomic integrity is common in chronic obstructive pulmonary disease (COPD) patients. The influence of the interaction between clinical and severity status on brain-heart autonomic axis (BHAA) is not well known. We aimed to investigate the BHAA function across different clinical status and severity of COPD.
Methods: Cross-sectional study involving 77 COPD patients allocated into four groups according to clinical status [acute exacerbation (GAE) or stable (GST)] and severity [less (-) or more (+)]: 1) GAE-, n = 13; 2) GAE+, n = 20; 3) GST-, n = 23; and 4) GST+, n = 21. Heart rate variability (HRV) at rest and heart rate recovery (HRR) after 6-min walk test were markers of BHAA. Mean R-R, STDRR, RMSSD, RRtri, HF, LF, SD1, SD2, ApEn and SampEn were the HRV indexes and, HRR was obtained as: HR at 1st min of recovery minus peak HR.
Results: A main effect of clinical status (p < 0.001) was found to vagal modulation in GAE-vs. GST- (RMSSD: 25.0 ± 14.8 vs. 12.6 ± 5.5 ms; SD1: 18.0 ± 10.6 vs. 8.9 ± 3.9 ms) and to GAE + vs. GST+ (RMSSD: 26.4 ± 15.2 vs. 15.4 ± 6.3 ms; SD1: 18.3 ± 11.2 vs. 10.9 ± 4.5 ms). An effect of clinical status (p = 0.032) and severity (p = 0.030) were found to HF (vagal) in GAE + compared to GAE- and GST+ (264.7 ± 239.0 vs. 134.7 ± 169.7 and 135.8 ± 139.7 ms2). Lower HRR was found in GAE-compared to GST- (8.0 ± 2.4 vs. 19.6 ± 2.4 bpm), p = 0.002.
Conclusion: In COPD patients, clinical status (AECOPD or stable) was more dominant than the severity on BHAA function. A more pronounced parasympathetic modulation was found in AECOPD patients with a lower HRR to exercise. | eng |
dc.description.sponsorship | Coordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES) | por |
dc.description.sponsorship | Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP) | por |
dc.language.iso | eng | eng |
dc.publisher | Universidade Federal de São Carlos | por |
dc.relation.uri | https://www.sciencedirect.com/science/article/pii/S0954611121002171 | por |
dc.relation.uri | https://repositorio.ufscar.br/handle/ufscar/13767 | por |
dc.rights | Attribution-NonCommercial-NoDerivs 3.0 Brazil | * |
dc.rights.uri | http://creativecommons.org/licenses/by-nc-nd/3.0/br/ | * |
dc.subject | Acute exacerbation | eng |
dc.subject | Autonomic nervous system | eng |
dc.subject | Exercise | eng |
dc.subject | Heart rate variability | eng |
dc.subject | Respiratory disease | eng |
dc.title | Brain-heart autonomic axis across different clinical status and severity of chronic obstructive pulmonary disease | eng |
dc.type | Dataset | eng |
dc.publisher.initials | UFSCar | por |
dc.publisher.program | Programa de Pós-Graduação em Fisioterapia - PPGFt | por |
dc.subject.cnpq | CIENCIAS DA SAUDE::FISIOTERAPIA E TERAPIA OCUPACIONAL | por |
dc.description.sponsorshipId | Processo nº 2015/26501–1, Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP) | por |
dc.description.sponsorshipId | Código de Financiamento 001 - CAPES | por |
dc.publisher.address | Câmpus São Carlos | por |
dc.contributor.authorlattes | http://lattes.cnpq.br/8573168804662842 | por |
dc.contributor.authorlattes | http://lattes.cnpq.br/4456979306195044 | por |
dc.contributor.authorlattes | http://lattes.cnpq.br/5075933151971198 | por |
dc.contributor.authorlattes | http://lattes.cnpq.br/8975177658472167 | por |
dc.contributor.authorlattes | http://lattes.cnpq.br/2731345085062145 | por |
dc.contributor.authorlattes | http://lattes.cnpq.br/0268406461810882 | por |
dc.contributor.authorlattes | http://lattes.cnpq.br/6818839151532121 | por |
dc.contributor.authorlattes | http://lattes.cnpq.br/8045534712864333 | por |
dc.contributor.authorlattes | http://lattes.cnpq.br/4855616925791895 | por |
dc.contributor.authorlattes | http://lattes.cnpq.br/9634590922242052 | por |
dc.publisher.department | Departamento de Fisioterapia - DFisio | por |