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Formação de complexos entre compostos híbridos pirrolbenzodiazepinas-cumarinas com DNA por estudos de docking molecular
(Universidade Federal de São Carlos, 2011-03-24)
Compounds of the pirrolbenzodiazepine (PBD) family are known for their promising antitumor activity. Among these, the hybrids, those that have a portion PDB a chain spacer and another functional group, such as the coumarins ...
Estabelecimento de metodologias de análise do DNA livre plasmático para o diagnóstico pré-natal não invasivo: sexagem fetal
(Universidade Federal de São Carlos, 2011-02-18)
In this paper we proposed and analyzed methodologies using the technology of Cell-Free Fetal Nucleic Acid-Free (cffDNA = Cell Free Fetal DNA) in noninvasive prenatal diagnosis (NIPD). Due to the modern technologies employed ...
Análise funcional dos genes xanB e xylA2 de Xanthomonas citri subsp. citri, agente causal do cancro cítrico
(Universidade Federal de São Carlos, 2020-02-20)
Xanthomonas citri subsp. citri (Xcc) is the main bacterium that causes citrus canker, a disease that affects all citrus cultivars of commercial interest, causing damages to the citrus sector due to the decrease in fruit ...
Docking molecular e interações não-covalentes de compostos originais derivados de 2-aril-oxazolinas em enzimas de Candida spp.
(Universidade Federal de São Carlos, 2019-08-23)
Candidiasis is a mycosis caused by fungi of the genus Candida spp. It affects up to 50% of the world's population and may progress to candidaemia, leading to death in up to a half of patients. Commercial drugs used in its ...