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Estabelecimento de metodologias de análise do DNA livre plasmático para o diagnóstico pré-natal não invasivo : sexagem fetal
(Universidade Federal de São Carlos, 2011-02-18)
In this paper we proposed and analyzed methodologies using the technology of Cell-Free Fetal Nucleic Acid-Free (cffDNA = Cell Free Fetal DNA) in noninvasive prenatal diagnosis (NIPD). Due to the modern technologies employed ...
Efeito anti-inflamatório do extrato etanólico da Harpagophytum procumbens durante a inflamação intestinal de camundongos infectados com Salmonella Enteritidis (ATCC13076)
(Universidade Federal de São Carlos, 2014-05-29)
Salmonellosis is an illness caused by bacteria of the genus Salmonella, a leading infectious disease worldwide. Due to the importance of this infection forward to eating habits, the search for a new compound that can ...
Mapeamento vetorial de interações eletrostáticas para biomoléculas
(Universidade Federal de São Carlos, 2013-04-15)
Non-covalent interactions involving aromatic rings pi, systems play an important role in a wide range of complexes. Their understanding is essential for drug design since most of the crystal structures of complexes of ...
Desenvolvimento de uma base de dados nacional para um instrumento automatizado de medidas do campo visual in vivo
(Universidade Federal de São Carlos, 2013-04-22)
Glaucoma is a leading cause of blindness in the elderly throughout the world. One of the most important diagnoses that is made in order to detect this pathology is a visual field perimetry, which measures the sensitivity ...
Estudos funcionais de uma possível cisteíno protease de Xanthomonas axonopodis pv. citri.
(Universidade Federal de São Carlos, 2007-02-27)
Cysteine proteases are enzymes found in many organisms and are
characterized by the presence of cysteine residue in their active site. These
proteases play an important role in the organism metabolism. In pathogenic
organisms, ...
Proposta de protocolos de segurança para a prevenção, a contenção e a neutralização de agente agressor bioativo em incidentes bioterroristas e estudo por docking molecular do fator letal do Bacillus anthracis (Antraz)
(Universidade Federal de São Carlos, 2010-10-29)
For centuries, infectious agents have been used as weapons in armed conflicts. In 1972 the Biological Weapons Convention prohibited the creation and stockpiling of biological weapons. However, some countries continued to ...
Estudos químicos e microbiológicos de microrganismos associados à esponja marinha Dragmacidon reticulatum, objetivando o isolamento de metabólitos secundários bioativos
(Universidade Federal de São Carlos, 2010-04-22)
Fungi are known as one of the most promising sources of unprecedent bioactive compounds, however, marine derived fungi are still very poorly studied. These microorganisms present high percentages of active metabolites and ...
Formação de complexos entre compostos híbridos pirrolbenzodiazepinas-cumarinas com DNA por estudos de docking molecular
(Universidade Federal de São Carlos, 2011-03-24)
Compounds of the pirrolbenzodiazepine (PBD) family are known for their promising antitumor activity. Among these, the hybrids, those that have a portion PDB a chain spacer and another functional group, such as the coumarins ...
Construção e caracterização cinética e fisiológica de um sistema células Sf9/ baculovírus recombinante para a produção de Canacistatina.
(Universidade Federal de São Carlos, 2007-03-14)
The development of the biotechnology has permitted to achieve, among other
biotechnological products, many recombinant proteins which are largely used as vaccines,
hormones, enzymes and other ways of human therapeutic ...
Caracterização do período de instabilidade de órgãos vegetais submetidos à injúria mecânica
(Universidade Federal de São Carlos, 2011-06-10)
Mechanical injuries are a major cause of post-harvest losses, since they may cause metabolic and physiological changes in fruit and vegetables. However there are few studies that characterize the state of the tissue after ...