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Caracterização de mutantes de Streptomyces clavuligerus ATCC 27064 obtidos por aplicação de radiação UV e tratamento químico
(Universidade Federal de São Carlos, 2008-12-18)
The clavulanic acid is a powerful inhibitor of the beta-lactamases produced by bacterias resistants to penicillin and cefalosporin. This acid is produced industrially by strains of Streptomyces clavuligerus in complex ...
Otimização das condições de cultivo de Erysipelothrix rhusiopathiae para produção de vacina contra erisipela suína
(Universidade Federal de São Carlos, 2007-03-30)
Swine erysipelas is one of the diseases responsible for the great economic losses in swine-producing areas of the world. The bacteria Erysipelothrix rhusiopathiae is the causative agent of erysipelas, and the vaccines ...
Os efeitos do Biosilicato® e do laser terapêutico de baixa potência no processo de consolidação em tíbias de ratos
(Universidade Federal de São Carlos, 2009-12-21)
Fractures of delayed consolidation and fractures with non-union are commonly found in medical practice and are associated with high morbidity and mortality. Within this context, biochemical and biophysical resource have ...
Inteligência computacional aplicada à automação de biorreator para produção de Penicilina G Acilase (PGA)
(Universidade Federal de São Carlos, 2008-07-11)
Biotechnology has presented, in the last years, a rapidly growing development. New biotechnological industrial processes are constantly introduced using different microorganisms and/or enzymes. In this context, the application ...
Estudo comparativo de precursores da PpIX (ALA e MAL) utilizados topicamente em terapia fotodinâmica
(Universidade Federal de São Carlos, 2008-08-08)
Photodynamic therapy (PDT) is a modality for treatment of tumors, and uses a combination of a drug (photosensitizer) and light in the presence of the molecular oxygen to selectively damage target tissue. In the absent of ...
Desenvolvimento de um oftalmoscópio binocular indireto com sistema eletrônico cromático de iluminação e módulo de aquisição de imagens
(Universidade Federal de São Carlos, 2009-05-13)
Chromatic contrast is a technique used in some areas of medicine to provide better visualization of biological tissues. Based on principles of color composition, a new illumination system was constructed using colored ...
Imobilização e estabilização de D-Hidantoinase para a produção de N-Carbamoil-D-Fenilglicina
(Universidade Federal de São Carlos, 2008-09-29)
Immobilization and stabilization of enzymes increases their potential for use in industrial scale. D-hydantoinases (dihidropirimidina amidrohidrolase EC 3.5.2.2) catalyze the hydrolysis of D-hydantoins, generating the ...
Avaliação de formas de preparação de estoques de trabalho na preservação de Streptomyces clavuligerus visando a produção de ácido clavulânico
(Universidade Federal de São Carlos, 2008-08-28)
A great deal of microbiological and genetic research in the pharmaceutical industry is directed towards the development of effective strategies in the handling of microorganisms
seeking the production of antibiotics that ...
Técnicas computacionais inteligentes para a inferência de estado e a otimização de cultivos de Streptococcus pneumoniae
(Universidade Federal de São Carlos, 2008-03-27)
Streptococcus pneumoniae (pneumococo) is a pathogenic bacterium that causes several infections which are aggravated by the increase of serotypes with antibiotics resistance. The development of an effective vaccine against ...
Desenvolvimento de um pipeline para análise genômica e transcriptômica com base em Web services
(Universidade Federal de São Carlos, 2009-09-04)
Pipeline systems for genomic and transcriptomic analysis aim to create communication bridges among the existing analysis tools, therefore reducing researchers efforts. Most of the pipelines found in the literature lack ...