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Hidrodinâmica e transferência de oxigênio em três biorreatores Airlift de circulação interna geometricamente semelhantes
(Universidade Federal de São Carlos, 2009-03-12)
Internal-loop airlift reactors (ALR) are a special class of pneumatic reactors. The use of this type of reactor has been attractive for chemical and biological reactions because of their simple construction without moving ...
Abordagem estatística e computacional na otimização de meios de cultura para produção de antibióticos: o caso da cefalosporina C.
(Universidade Federal de São Carlos, 2003-10-10)
The scope of the current work was to investigate the effect of glucose, amonium acetate, DL-methionine, phosphorus, oleic acid and salt solution on the maximum specific growth rate (µmax), as well as the effect of sucrose ...
Separação de ampicilina produzida enzimaticamente por reação entre éster metílico de fenilglicina e ácido 6-aminopenicilânico.
(Universidade Federal de São Carlos, 2003-11-07)
The separation/concentration process of the products obtained from the enzymatic synthesis of ampicillin (AMP) catalyzed by immobilized penicillin G acylase was the focus of this Thesis. Hydrophobic resin adsorption and ...
Produção de xilo-oligossacarídeos a partir de lignocelulósicos pré-tratados com xilanases imobilizadas e estabilzadas
(Universidade Federal de São Carlos, 2012-02-28)
Endoxylanase, an important industrial enzyme, cleaves ß-1,4-xylanosidic bounds in xylan chains, main plant hemicellulose component. Xylan can be explored to produce many products, among them xylo-oligosaccharides, XOS, ...
Inferência de variáveis do processo de produção de penicilina G acilase por Bacillus megaterium ATCC-14945.
(Universidade Federal de São Carlos, 2003-07-27)
The enzyme penicillin G acylase (E.C.3.5.1.11) is used in the production of 6-aminopenicillanic acid (6-APA) and 7-aminocephalosporinic acid (7-ACA), which are key intermediates for the production of β-lactam antibiotics. ...
Estudo da purificação do àcido clavulânico utilizando processo contínuo de adsorsão.
(Universidade Federal de São Carlos, 2003-10-02)
Clavulanic acid (CA), a beta-lactam antibiotic, has been known for its commercial and therapeutic importance. This antibiotic is produced by an actinomicete, Streptomyces clavuligerus, and has a combined use with penicillins, ...
Estratégias para melhoria da produção de ácido clavulânico por Streptomyces clavuligerus
(Universidade Federal de São Carlos, 2014-02-27)
Clavulanic acid (CA) produced by Streptomyces clavuligerus, is a potent inhibitor of beta-lactamases used in combination with conventional beta-lactam antibiotics in the treatment of infections caused by resistant bacteria ...
Extração de cefamicina C por sistema de duas fases aquosas e purificação por troca iônica
(Universidade Federal de São Carlos, 2013-04-26)
Cephamycin C is a β-lactam antibiotic that belongs to the cephalosporins. This antibiotic stands out from other cephalosporins because it has activity against gram-negative bacteria and for being resistent to ...
Produção, isolamento e identificação de metabólito com atividade citotóxica de cultura de Streptomyces carpaticus
(Universidade Federal de São Carlos, 2011-09-21)
This study addresses the production, isolation and identification of the substance present in culture broth of Streptomyces carpaticus which showed high biological activity against human tumor cell lines HL-60 (promyelocytic ...
Transferência de oxigênio e condições de cisalhamento em biorreator convencional com impelidores orelha de elefante
(Universidade Federal de São Carlos, 2013-09-30)
Due to owing to the nature of culture involving aerobic filamentous microorganisms, conventional aerated stirred-tank bioreactors using the Rushton turbine impeller are widely employed in order to achieve good mixing and ...