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Hidrodinâmica e transferência de oxigênio em três biorreatores Airlift de circulação interna geometricamente semelhantes
(Universidade Federal de São Carlos, 2009-03-12)
Internal-loop airlift reactors (ALR) are a special class of pneumatic reactors. The use of this type of reactor has been attractive for chemical and biological reactions because of their simple construction without moving ...
Abordagem estatística e computacional na otimização de meios de cultura para produção de antibióticos: o caso da cefalosporina C.
(Universidade Federal de São Carlos, 2003-10-10)
The scope of the current work was to investigate the effect of glucose, amonium acetate, DL-methionine, phosphorus, oleic acid and salt solution on the maximum specific growth rate (µmax), as well as the effect of sucrose ...
Separação de ampicilina produzida enzimaticamente por reação entre éster metílico de fenilglicina e ácido 6-aminopenicilânico.
(Universidade Federal de São Carlos, 2003-11-07)
The separation/concentration process of the products obtained from the enzymatic synthesis of ampicillin (AMP) catalyzed by immobilized penicillin G acylase was the focus of this Thesis. Hydrophobic resin adsorption and ...
Inferência de variáveis do processo de produção de penicilina G acilase por Bacillus megaterium ATCC-14945.
(Universidade Federal de São Carlos, 2003-07-27)
The enzyme penicillin G acylase (E.C.3.5.1.11) is used in the production of 6-aminopenicillanic acid (6-APA) and 7-aminocephalosporinic acid (7-ACA), which are key intermediates for the production of β-lactam antibiotics. ...
Avaliação de transferência de calor e massa em biorreator Airlift de bancada para a produção de ácido clavulânico.
(Universidade Federal de São Carlos, 2005-03-28)
The importance of the airlift bioreactor has grown in the biotechnology
field by aspects as high oxygen transfer, with power input low.
In this work were study the conditions heat and mass transfer, as well
as the condenser ...
Estudo da expressão de lipase BTL2 de Bacillus thermocatenulatus em E. coli recombinante
(Universidade Federal de São Carlos, 2009-04-03)
Using recombinant DNA techniques, the lipase BTL2 gene of Bacillus thermocatenulatus was cloned in E. coli BL321 under control of the strong temperature-inducible λPL promoter. It
was investigated, initially, in this ...
Contribuição ao desenvolvimento de metodologia para detecção de desintegrina recombinante produzida em cultivos de células CHO-K1.
(Universidade Federal de São Carlos, 2004-06-25)
Disintegrins are proteins present in the poison of serpents that have been calling the pharmaceutical industry attention due to their capacity to prevent the progression of cancerous cells. A receiving key-protein called ...
Desenvolvimento e otimização do processo fermentativo para a produção de vinho branco a partir da uva Itália.
(Universidade Federal de São Carlos, 2005-08-19)
With the reduction of vineyards in São Roque, the wine industry of this region has been seeking for alternatives to produce common wine with low cost. In the present work, wine production from Italia grape obtained at the ...
Avaliação de variáveis operacionais e aplicação de enfoque híbrido na modelagem do processo de produção de penicilina G acilase por Bacillus megaterium.
(Universidade Federal de São Carlos, 2005-09-08)
In the present work it was studied the influence of operational conditions particularly dissolved oxygen concentration in the penicillin G acylase (PGA) production. The
experiments were carried out in aerated and agitated ...
Avaliação diferencial de fatores fisiológicos e cinéticos em cultivos de linhagens de células selvagem e recombinante de Drosophila melanogaster S2
(Universidade Federal de São Carlos, 2005-09-19)
In the last 10 years the insect cell Drosophila melanogaster Schneider S2 has been increasingly used for studies of proteins recombinants. However, there is a lack of studies that involved parameters related to the use of ...