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Inovação nas condições de cultivo visando o melhoramento da produção de vacina contra erisipela suína
(Universidade Federal de São Carlos, 2010-03-19)
Pork is one of the most widely eaten meats in the world and pig farming is an economic activity booming in Brazil and the world. Several efforts have been made to develop more effective vaccines for major diseases that are ...
Otimização do cultivo de Bacillus megaterium recombinante em bateladas alimentadas
(Universidade Federal de São Carlos, 2010-03-31)
Penicillin Acylases are enzymes of great industrial importance, being used mainly for production of 6-aminopenicillanic acid, 6-APA from penicillin G. In the late 90's, its use for synthesis of β-lactam semisynthetic ...
Produção de ácido clavulânico por Streptomyces clavuligerus em cultivos em batelada e batelada alimentada com pulsos de glicerol sob diferentes condições de temperatura
(Universidade Federal de São Carlos, 2010-03-25)
The production of enzymes β-lactamases by pathogenic bacteria is the most common mechanism of resistance to β-lactam antibiotics. The β-lactamases catalyze the hydrolysis of β-lactam ring, splitting the ...
Otimização dinâmica do cultivo semi-contínuo de Pichia pastoris recombinante para produção das enzimas heterólogas alfa amilase e penicilina G acilase
(Universidade Federal de São Carlos, 2010-03-31)
This master's thesis project aims at studying the dynamic optimization of the operation of a bench scale (up to 5L) automated, agitated and aerated bioreactor, where the semi-continuous cultivation of recombinant Pichia ...