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Estudo da purificação do àcido clavulânico utilizando processo contínuo de adsorsão.
(Universidade Federal de São Carlos, 2003-10-02)
Clavulanic acid (CA), a beta-lactam antibiotic, has been known for its commercial and therapeutic importance. This antibiotic is produced by an actinomicete, Streptomyces clavuligerus, and has a combined use with penicillins, ...
Separação e purificação do ácido clavulânico através de extração líquido-líquido seguida de adsorção em coluna de leito fixo.
(Universidade Federal de São Carlos, 2005-10-19)
A study was made of the extraction of clavulanic acid (CA) from a fermented medium and
its concentration and purification, based on a comparison of two liquid-liquid extraction
methods, followed by adsorption in a fixed ...
Produção de ácido clavulânico por Streptomyces clavuligerus em cultivos em batelada e batelada alimentada com pulsos de glicerol sob diferentes condições de temperatura
(Universidade Federal de São Carlos, 2010-03-25)
The production of enzymes β-lactamases by pathogenic bacteria is the most common mechanism of resistance to β-lactam antibiotics. The β-lactamases catalyze the hydrolysis of β-lactam ring, splitting the ...
Avaliação de transferência de calor e massa em biorreator Airlift de bancada para a produção de ácido clavulânico.
(Universidade Federal de São Carlos, 2005-03-28)
The importance of the airlift bioreactor has grown in the biotechnology
field by aspects as high oxygen transfer, with power input low.
In this work were study the conditions heat and mass transfer, as well
as the condenser ...
Estratégias para melhoria da produção de ácido clavulânico por Streptomyces clavuligerus
(Universidade Federal de São Carlos, 2014-02-27)
Clavulanic acid (CA) produced by Streptomyces clavuligerus, is a potent inhibitor of beta-lactamases used in combination with conventional beta-lactam antibiotics in the treatment of infections caused by resistant bacteria ...
Transferência de oxigênio e condições de cisalhamento em biorreator convencional com impelidores orelha de elefante
(Universidade Federal de São Carlos, 2013-09-30)
Due to owing to the nature of culture involving aerobic filamentous microorganisms, conventional aerated stirred-tank bioreactors using the Rushton turbine impeller are widely employed in order to achieve good mixing and ...