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Now showing items 11-20 of 22
Contribuição ao desenvolvimento de metodologia para detecção de desintegrina recombinante produzida em cultivos de células CHO-K1.
(Universidade Federal de São Carlos, 2004-06-25)
Disintegrins are proteins present in the poison of serpents that have been calling the pharmaceutical industry attention due to their capacity to prevent the progression of cancerous cells. A receiving key-protein called ...
Estudo da cinética e do equilíbrio da adsorção da cefamicina C em resina de troca iônica e simulação do processo contínuo
(Universidade Federal de São Carlos, 2011-03-01)
The cephamycin C (CefC) is a beta-lactam antibiotic produced from submerged and aerated cultures of Streptomyces clavuligerus. Acts as inhibitor of cell wall formation of Gram-negative bacteria and is resistant to the ...
Produção de ácido clavulânico por Streptomyces clavuligerus em cultivos em batelada e batelada alimentada com pulsos de glicerol sob diferentes condições de temperatura
(Universidade Federal de São Carlos, 2010-03-25)
The production of enzymes β-lactamases by pathogenic bacteria is the most common mechanism of resistance to β-lactam antibiotics. The β-lactamases catalyze the hydrolysis of β-lactam ring, splitting the ...
Otimização dinâmica do cultivo semi-contínuo de Pichia pastoris recombinante para produção das enzimas heterólogas alfa amilase e penicilina G acilase
(Universidade Federal de São Carlos, 2010-03-31)
This master's thesis project aims at studying the dynamic optimization of the operation of a bench scale (up to 5L) automated, agitated and aerated bioreactor, where the semi-continuous cultivation of recombinant Pichia ...
Avaliação de transferência de calor e massa em biorreator Airlift de bancada para a produção de ácido clavulânico.
(Universidade Federal de São Carlos, 2005-03-28)
The importance of the airlift bioreactor has grown in the biotechnology
field by aspects as high oxygen transfer, with power input low.
In this work were study the conditions heat and mass transfer, as well
as the condenser ...
Desenvolvimento e otimização do processo fermentativo para a produção de vinho branco a partir da uva Itália.
(Universidade Federal de São Carlos, 2005-08-19)
With the reduction of vineyards in São Roque, the wine industry of this region has been seeking for alternatives to produce common wine with low cost. In the present work, wine production from Italia grape obtained at the ...
Avaliação de variáveis operacionais e aplicação de enfoque híbrido na modelagem do processo de produção de penicilina G acilase por Bacillus megaterium.
(Universidade Federal de São Carlos, 2005-09-08)
In the present work it was studied the influence of operational conditions particularly dissolved oxygen concentration in the penicillin G acylase (PGA) production. The
experiments were carried out in aerated and agitated ...
Purificação de penicilina G acilase produzida por Escherichia coli e Bacillus megaterium recombinantes
(Universidade Federal de São Carlos, 2014-03-28)
Penicillin G acylase (PGA) is the key enzyme for the industrial production of β-lactam antibiotics. Major current PGA demand is attended for producer organisms as Escherichia coli and Bacillus megaterium genetically ...
Avaliação da expansão de células estromais mesenquimais em biorreator de fibra oca
(Universidade Federal de São Carlos, 2013-02-28)
The use of mesenchymal stromal cells (MSCs) for clinical therapy has been limited by the low amount of cells that can be obtained directly from tissue, making it necessary to develop techniques for in vitro cell number ...
Avaliação da produção de ciclodextrina glicosiltransferase (CGTase) por fermentação submersa de Paenibacillus sp.
(Universidade Federal de São Carlos, 2014-03-31)
Cyclodextrins (CDs) are cyclic oligosaccharides that show the ability to encapsulate a large number of organic molecules at the molecular level. Thus, they have large application in pharmaceutical, food, and cosmetics ...