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Efeito das enzimas recombinantes de Schistosoma mansoni Hipoxantina-Guanina Fosforibosiltransferase (HGPRT) e Purina Nucleosídeo Fosforilase (PNP) no tratamento da esquistossomose experimental
(Universidade Federal de São Carlos, 2018-02-26)
Schistosomiasis is a disease that affects a large number of people in 78 countries. The
number of cases has increased in recent years and there is no vaccine and new drugs, a
worrying aspect, since there is loss of ...
Deleção oócito-específica da Rad51 em murinos e seu impacto sobre a função mitocondrial e a fertilidade
(Universidade Federal de São Carlos, 2020-02-14)
One of the first signs of aging in humans is the decrease in female fertility, which is
accompanied by a reduction in the expression of proteins that integrate the Double Strand Break
(DSB) repair machinery, such as ...
Utilizando ferramentas da genética forense para investigar a origem dos indivíduos do canário-da-terra (Sicalis flaveola) mantidos em cativeiro
(Universidade Federal de São Carlos, 2020-03-31)
Wildlife protection is a global priority issue. International treaties, laws, national entities and organizations fight for the conservation of biodiversity and protection of wildlife, generating environmental awareness ...
Variantes reguladoras associadas à expressão alelo-específica (aseQTL) em músculo de Nelore (Bos indicus)
(Universidade Federal de São Carlos, 2020-02-27)
Brazil is a significant exporter of beef, so the improvement of Nelore, a breed mostly present
in the Brazilian herd, directly impact this sector. Genomic tools can identify SNPs associated
with interesting livestock ...
Impacto da deleção oócito-específica de Rad51 sobre o DNA mitocondrial e a divisão meiótica em murinos
(Universidade Federal de São Carlos, 2020-02-28)
RAD51 is a protein of eukaryotic organisms, with a central role in the DNA repair pathway by homologous recombination. Its function in the nucleus of somatic cells is well established, being necessary for the maintenance ...
Montagem e análise taxonômica-funcional de transcriptomas de espécies de cupins brasileiros
(Universidade Federal de São Carlos, 2020-02-28)
Termites (Isoptera) are eusocial insects that stand out for their hierarchical and structural organization, demonstrating complex social behaviors, numerous symbiotic interactions, and a great potential for bioprospecting ...
Diversidade genética e estruturação populacional do tatu-canastra (Priodontes maximus) em uma área do Centro-Oeste do Brasil
(Universidade Federal de São Carlos, 2020-03-30)
The giant armadillo, Priodontes maximus, is a neotropical mammal that belongs to the Xenarthra superorder. The species is widely distributed in nine countries in South America. Although its distribution is wide, it occurs ...
Análises bioinformáticas de proteínas de resistência do tipo nucleotide binding site-leucine rich repeat (NBS-LRR) de café
(Universidade Federal de São Carlos, 2019-02-15)
The molecular factors involved in the coffee’s resistance to rust and other diseases have not been completely known, but related projects have been developed since the last century. One of the main problems that make ...
Clonagem e expressão heteróloga de proteínas estruturais (C, prM, E) de Zika Virus (ZIKV)
(Universidade Federal de São Carlos, 2018-08-31)
Viruses are organisms which depend on the host cellular machinery to replicate,
and are relevant to human, livestock and plant health. The modern threat of emerging
pandemics is pressing and, in this scenario, Zika Virus ...
Validação de kit imunocromatográfico rápido para diagnóstico da Hepatite C
(Universidade Federal de São Carlos, 2019-09-17)
Hepatitis C is an infectious disease caused by the Hepatitis C Virus (HCV) and usually asymptomatic in the acute phase. Globally, an estimated 71 million people are infected with HCV and approximately 400,000 deaths happen ...