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Identificação e clonagem de genes espécie-específicos de Leishmania infantum para expressão piloto de proteínas recombinantes com potencial para o diagnóstico de Leishmaniose Visceral
(Universidade Federal de São Carlos, 2023-02-16)
Leishmaniasis is a public health problem observed in several countries, being considered by the World Health Organization (WHO) one of the 10 neglected tropical diseases. It is caused by Leishmania parasites that affect ...
Expressão recombinante e ensaios de atividade de duas thaumatin-like proteins do Maqui (Aristotelia chilensis)
(Universidade Federal de São Carlos, 2022-10-24)
Thaumatin-like Proteins (TLP) are members of the Pathogenesis-Related Proteins family 5 (PR-5), and are present in fungi, plants and invertebrates. In plants, these proteins are involved both in the host’s defense, often ...
Efeito da microvibração sobre a produção in vitro de embriões bovinos
(Universidade Federal de São Carlos, 2022-11-07)
Much effort has been employed to improve the quality of embryos obtained by in vitro production (IVP) given the relevance of this technology to current livestock systems. In this context, dynamic IVP systems have been shown ...
Cistatinas de maqui: produção recombinante e inibição de cisteíno peptidases
(Universidade Federal de São Carlos, 2022-02-15)
Cystatins are tight binding competitive inhibitors of cysteine peptidases. In plants, they act regulating different physiological mechanisms, as well as defending from biotic and abiotic stresses, making them of potential ...
Seleção e caracterização molecular e fermentativa de leveduras personalizadas para a produção de vinhos brasileiros
(Universidade Federal de São Carlos, 2022-03-04)
Brazilian wine production has been standing out with high quality awarded wines around the world. However, major changes are still needed so that our country can compete with other wineries in the world. Among them, we can ...
Estudo do efeito do silenciamento do gene ITGB3 em células tumorais de mama
(Universidade Federal de São Carlos, 2022-09-01)
Breast cancer is the major disease that affects women, especially the triple negative phenotype, which has the worst prognosis and metastatic potential. Included, metastasis is still the main cause of death in cancer ...
Utilizando ferramentas da genética forense para investigar a origem dos indivíduos do canário-da-terra (Sicalis flaveola) mantidos em cativeiro
(Universidade Federal de São Carlos, 2020-03-31)
Wildlife protection is a global priority issue. International treaties, laws, national entities and organizations fight for the conservation of biodiversity and protection of wildlife, generating environmental awareness ...
Impacto da deleção oócito-específica de Rad51 sobre o DNA mitocondrial e a divisão meiótica em murinos
(Universidade Federal de São Carlos, 2020-02-28)
RAD51 is a protein of eukaryotic organisms, with a central role in the DNA repair pathway by homologous recombination. Its function in the nucleus of somatic cells is well established, being necessary for the maintenance ...
Montagem e análise taxonômica-funcional de transcriptomas de espécies de cupins brasileiros
(Universidade Federal de São Carlos, 2020-02-28)
Termites (Isoptera) are eusocial insects that stand out for their hierarchical and structural organization, demonstrating complex social behaviors, numerous symbiotic interactions, and a great potential for bioprospecting ...
Efeitos citotóxicos e genotóxicos de uma nova nanopartícula de titânio de interesse industrial - in vitro
(Universidade Federal de São Carlos, 2020-02-18)
Titanium dioxide nanoparticles (TiO2 NP) are included as one of the most used nanomaterials by industries in general; it is applied in coatings, pigments, and paints for its ability to offer opacity and brightness, in ...