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Mapeamento proteico da matriz do esmalte de incisivos de camundongos susceptíveis e resistentes à fluorose dentária
(Universidade Federal de São Carlos, 2015-08-12)
Enamel formation is a two-step complex process by which proteins are first secreted to forming an extracellular matrix, followed by massive protein degradation simultaneously with the completion of mineralization. Excessive ...
Expressão recombinante e ensaios de atividade de duas thaumatin-like proteins do Maqui (Aristotelia chilensis)
(Universidade Federal de São Carlos, 2022-10-24)
Thaumatin-like Proteins (TLP) are members of the Pathogenesis-Related Proteins family 5 (PR-5), and are present in fungi, plants and invertebrates. In plants, these proteins are involved both in the host’s defense, often ...
Efeito da microvibração sobre a produção in vitro de embriões bovinos
(Universidade Federal de São Carlos, 2022-11-07)
Much effort has been employed to improve the quality of embryos obtained by in vitro production (IVP) given the relevance of this technology to current livestock systems. In this context, dynamic IVP systems have been shown ...
Potencial antitumoral das proteínas TRAIL e IL-2 expressas e veiculadas por Salmonella Typhimurium atenuada em modelo de câncer colorretal
(Universidade Federal de São Carlos, 2019-10-14)
Colorectal cancer is the third most diagnosed malignant disease and the fourth leading cause of cancer-related deaths in the world. Cancer treatments are not fully effective and low selectivity to tumor tissue has marked ...
Seleção e caracterização molecular e fermentativa de leveduras personalizadas para a produção de vinhos brasileiros
(Universidade Federal de São Carlos, 2022-03-04)
Brazilian wine production has been standing out with high quality awarded wines around the world. However, major changes are still needed so that our country can compete with other wineries in the world. Among them, we can ...
Estudo do efeito do silenciamento do gene ITGB3 em células tumorais de mama
(Universidade Federal de São Carlos, 2022-09-01)
Breast cancer is the major disease that affects women, especially the triple negative phenotype, which has the worst prognosis and metastatic potential. Included, metastasis is still the main cause of death in cancer ...
Caracterização funcional e bioquímica do fator de transcrição rlmA e da interação de PkcA e Hsp90 no fungo Aspergillus fumigatus
(Universidade Federal de São Carlos, 2017-12-18)
Aspergillus fumigatus is an opportunistic human pathogen that causes systemic infections, including invasive pulmonary aspergillosis in immunocompromised individuals. Survival of this fungus is highly dependent on the cell ...
Análise da expressão gênica e conteúdo proteico de ABCB10, APEX1 e HMGB1 em pacientes com beta talassemia maior e intermediaria
(Universidade Federal de São Carlos, 2017-09-04)
Beta thalassemias (BT) are a group of hereditary diseases characterized by the partial or total suppression of beta globin chains synthesis. Clinically, it manifests itself in three distinct forms: minor (BTm), intermedia ...
Degradação de matéria orgânica terrestre por microrganismos do rio Amazonas – Metagenômica e genômica populacional
(Universidade Federal de São Carlos, 2018-12-14)
Microbes from Amazon river basin represent an unexplored biodiversity, with a huge metabolic potential. This ecosystem receives large amounts of terrestrial organic matter (OM), which promotes heterotrophic microbial growth. ...
Utilizando ferramentas da genética forense para investigar a origem dos indivíduos do canário-da-terra (Sicalis flaveola) mantidos em cativeiro
(Universidade Federal de São Carlos, 2020-03-31)
Wildlife protection is a global priority issue. International treaties, laws, national entities and organizations fight for the conservation of biodiversity and protection of wildlife, generating environmental awareness ...