SCF complexes are composed by Skp1, Cullin1, Rbx1 and an F-box protein (FBP), which are responsible to give specificity to the complexes, as they interact with substrates, allowing ligation of an ubiquitin molecule to the ...

Parasitism by gastrointestinal nematodes, mainly by Haemonchus contortus, is the major obstacle to sheep production. Anthelmintic treatment is the main method used by farmers to control worms. However, parasites acquire ...

Viruses are organisms which depend on the host cellular machinery to replicate, and are relevant to human, livestock and plant health. The modern threat of emerging pandemics is pressing and, in this scenario, Zika Virus ...

Currently the number of works that seek to understand the difficulties involved in the teaching and learning process in Biology field, more specifically in the Molecular Biology subfield, has been grown exponentially. Such ...

The family Crabronidae comprises a group of extreme importance to the phylogeny of Hymenopytera and is considered by some authors to be the group that gave rise to bees. Despite this importance, very few studies have been ...

Fertility is directly related to oocyte developmental competence. In this context, oocyte mitochondria play a crucial role and have become an important target in assisted reproduction therapies. However, the molecular ...

Sugarcane rust (Puccinia melanocephala) is a major disease distributed throught the world, causing yield losses of 50% in conducive environments. Resistance is an essential trait to control rust in commercial cultivars ...

The desintegrinas are cys-rich polypeptides without enzymatic activity, some found in snake venoms with an adhesive motif to integrin, unleashing distinct responses. Several research groups have been studying snake venom ...

Cancer metastasis is the major cause of death, consequently studies to understand the molecular mechanisms involved in this process are essential to the knowledge of this disease. Cell migration and invasion are part of ...

Disintegrins are snake venom protein, of low molecular weight, rich in cysteines and RGDcontaining peptides that bind specifically to integrins αIIbβ3, α5β1, and αvβ3 expressed on platelets, ...