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Efeito citotóxico e pró-apoptótico do composto [6]-Shogaol contra células de câncer de bexiga (MB49), in vitro
(Universidade Federal de São Carlos, 2021-05-24)
Bladder cancer is considered one of the most aggressive malignancies due to its profile of recurrence and progression, and even with the improvement in methods of diagnosis and treatment, the mortality rate has not shown ...
Análise dos transcriptomas de Paspalum notatum Flúggé e Paspalum vaginatum Swartz em condição de déficit hídrico
(Universidade Federal de São Carlos, 2020-02-19)
Drought is one of the abiotic stresses that most affect plant growth and productivity. Grasses of the genus Paspalum are used successfully in pastures and lawns, and some ecotypes of Paspalum notatum (bahiagrass) have good ...
Clonagem e caracterização das isoformas de luciferases de lanternas e corpo gorduroso do vagalume Aspisoma lineatum (Lampyridae: Cratomorphini): origem estrutural e evolutiva das luciferases pH-sensitivas mais eficientes à partir de ancestrais pH-insensitivas
(Universidade Federal de São Carlos, 2020-10-31)
Firefly luciferases emit yellow-green light with high efficiency at physiological pH. However, under acidic conditions, in the presence of heavy metals or high temperatures, they emit red light. To understand the structural ...
Estudo dos efeitos antiangiogênicos da desintegrina-símile Alternagina-C (ALT-C) em células endoteliais (HUVEC), tendo como alvo a integrina α2β1
(Universidade Federal de São Carlos, 2020-03-04)
Angiogenesis is a crucial process in tumor progression, and it is mainly regulated by the vascular endothelial growth factor (VEGF) and its receptor, VEGFR2. Studies have shown that VEGF/VEGFR2 axis signaling is directly ...