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Now showing items 11-20 of 127
Análise do transcriptoma da glândula venenífera de Rhinocerophis alternatus (Bothrops alternatus): identificação de metaloproteases e desintegrinas
(Universidade Federal de São Carlos, 2011-03-04)
The desintegrinas are cys-rich polypeptides without enzymatic activity, some found in snake venoms with an adhesive motif to integrin, unleashing distinct responses. Several research groups have been studying snake venom ...
Papel do domínio desintegrina da ADAM9 humana na modulação da migração e invasão de células tumorais
(Universidade Federal de São Carlos, 2011-02-25)
Cancer metastasis is the major cause of death, consequently studies to understand the molecular mechanisms involved in this process are essential to the knowledge of this disease. Cell migration and invasion are part of ...
Clonagem e expressão heteróloga de proteínas estruturais (C, prM, E) de Zika Virus (ZIKV)
(Universidade Federal de São Carlos, 2018-08-31)
Viruses are organisms which depend on the host cellular machinery to replicate,
and are relevant to human, livestock and plant health. The modern threat of emerging
pandemics is pressing and, in this scenario, Zika Virus ...
Análises bioinformáticas de proteínas de resistência do tipo nucleotide binding site-leucine rich repeat (NBS-LRR) de café
(Universidade Federal de São Carlos, 2019-02-15)
The molecular factors involved in the coffee’s resistance to rust and other diseases have not been completely known, but related projects have been developed since the last century. One of the main problems that make ...
Validação de kit imunocromatográfico rápido para diagnóstico da Hepatite C
(Universidade Federal de São Carlos, 2019-09-17)
Hepatitis C is an infectious disease caused by the Hepatitis C Virus (HCV) and usually asymptomatic in the acute phase. Globally, an estimated 71 million people are infected with HCV and approximately 400,000 deaths happen ...
Investigação da diversificação e evolução cromossômica em espécies de Pimelodidae (Siluriformes): contribuição dos DNAs repetitivos e cromossomos B
(Universidade Federal de São Carlos, 2019-02-18)
Pimelodidae comprises 114 valid species, whith few of them are cytogenetically characterized, mainly, especially with respect to molecular cytogenetics. In addition, the species taxonomic delimitation is still very imprecise ...
Caracterização funcional parcial de dois genes de Xanthomonas citri potencialmente relacionados com a patogenicidade: XAC1006 (malato desidrogenase) e XAC0223 (proteína hipotética conservada)
(Universidade Federal de São Carlos, 2019-02-12)
The bacterium Xanthomonas citri subsp. citri (XAC) is the cause of citrus canker, a disease that affects many species of citric plants, causing drop in productivity and losses to producers. Many proteins have been detected ...
Efeito das enzimas recombinantes de Schistosoma mansoni Hipoxantina-Guanina Fosforibosiltransferase (HGPRT) e Purina Nucleosídeo Fosforilase (PNP) no tratamento da esquistossomose experimental
(Universidade Federal de São Carlos, 2018-02-26)
Schistosomiasis is a disease that affects a large number of people in 78 countries. The
number of cases has increased in recent years and there is no vaccine and new drugs, a
worrying aspect, since there is loss of ...
Inibidores de poligalacturonase (PGIPs) oriundos do feijão: produção recombinante e estudos funcionais
(Universidade Federal de São Carlos, 2019-03-01)
Pectic substances are components of the middle lamella of the plant cell wall and are composed of partially methyl-esterified galacturonic acid residues linked by α-1,4 glycosidic bonds. These substances are naturally ...
Avaliação de potenciais antígenos vacinais e geração de aptâmeros por cell-SELEX em Erysipelothrix rhusiopathiae
(Universidade Federal de São Carlos, 2018-02-28)
Erysipelothrix rhusiopathiae is a Gram-positive bacterium that causes the disease known as swine erysipelas. Available veterinary vaccines against the disease have several limitations and methods for detecting the bacterium ...