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Efeitos citotóxicos e genotóxicos de uma nova nanopartícula de titânio de interesse industrial - in vitro
(Universidade Federal de São Carlos, 2020-02-18)
Titanium dioxide nanoparticles (TiO2 NP) are included as one of the most used nanomaterials by industries in general; it is applied in coatings, pigments, and paints for its ability to offer opacity and brightness, in ...
Evolução cromossômica na família Lebiasinidae (Teleostei, Characiformes), com enfoque em espécies do gênero Lebiasina
(Universidade Federal de São Carlos, 2020-02-06)
The Lebiasinidae family is composed by seven genus of small freshwater fishes that can be found in small rivers of Central and South America. Members of this family presents a great diversity in form and body color, but ...
Efeitos das desintegrinas Alternagina-C e DisBa-01 de Bothrops alternatus em fibroblastos, células endoteliais e tumorais
(Universidade Federal de São Carlos, 2009-11-17)
Disintegrins are small cysteine-rich proteins with an RGD motif isolated from viperidae snake venoms. DisBa-01, a recombinant RGD-disintegrin from Bothrops alternatus snake venom, inhibits melanoma cell metastasis and also ...
Triagem de isolados clínicos de Leishmania sp. para sequenciamento genômico
(Universidade Federal de São Carlos, 2020-06-22)
Leishmaniasis is a group of infectious tropical disease caused by protozoan from genus Leishmania and transmitted to humans through bites of infected sand flies. Visceral Leishmaniasis (VL) is the most severe clinical form ...
Investigação dos mecanismos envolvidos na herança mitocondrial: o papel da dinâmica mitocondrial
(Universidade Federal de São Carlos, 2020-10-08)
Diseases caused by mutations in mitochondrial DNA (mtDNA) are the most common genetic diseases in humans. Despite this, there is no effective treatment for these diseases and the mechanisms of inheritance are not fully ...
Eficácia da instilação de células da linhagem MB49 e gel polimérico termorreversível na imunização contra o carcinoma urotelial de bexiga
(Universidade Federal de São Carlos, 2020-09-24)
Among the various types of malignant neoplasms, those originating in the bladder can be considered highly impactful due to their prevalence and high recurrence rates, demonstrating the importance of studies involving new ...
Viabilidade de grãos de pólen de espécies de Paspalum após a criopreservação visando seu uso em programas de melhoramento genético
(Universidade Federal de São Carlos, 2020-02-28)
Paspalum is a genus of the Poaceae family, native to America, of which many species have forage potential. The high natural genetic diversity observed in the genus can be used to obtain and launch new cultivars. For ...
Análise dos transcriptomas de Paspalum notatum Flúggé e Paspalum vaginatum Swartz em condição de déficit hídrico
(Universidade Federal de São Carlos, 2020-02-19)
Drought is one of the abiotic stresses that most affect plant growth and productivity. Grasses of the genus Paspalum are used successfully in pastures and lawns, and some ecotypes of Paspalum notatum (bahiagrass) have good ...
Estudo dos efeitos antiangiogênicos da desintegrina-símile Alternagina-C (ALT-C) em células endoteliais (HUVEC), tendo como alvo a integrina α2β1
(Universidade Federal de São Carlos, 2020-03-04)
Angiogenesis is a crucial process in tumor progression, and it is mainly regulated by the vascular endothelial growth factor (VEGF) and its receptor, VEGFR2. Studies have shown that VEGF/VEGFR2 axis signaling is directly ...
Citogenética comparativa em espécies de Hypostomus (Siluriformes, Loricariidae, Hypostominae). Contribuição da fração repetitiva do genoma para a diversidade cromossômica do grupo
(Universidade Federal de São Carlos, 2012-11-14)
Hypostomus is the widest genus of the armored catfishes in South America. This group presents a great diversity in color pattern and morphology, and shows not conservative chromosomal features. Different classes of repetitive ...