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Estudos das proteínas ligantes à DCRA e DSCR1 (envolvidas com a síndrome de Down) utilizando a metodologia do duplo-híbrido.
(Universidade Federal de São Carlos, 2003-01-24)
The genes DCRA and DSCR1 are located in the Down Syndrome Critical Region , a specific portion of human chromosome 21 responsible for the main traits of the disease. In the present work we have used the two-hybrid system ...
Estudos moleculares da Selenocisteína Sintase (SELA) de Escherichia coli.
(Universidade Federal de São Carlos, 2005-05-05)
The study of translation processes attracts the interest of a wide range of
research groups due to its main role in general cellular metabolism. In
particular, the investigation of new amino acid residues, such as ...
Expressão heteróloga, purificação e estudo de atividade de uma proteína inibidora de cisteínio protease da cana-de-açúcar e posterior evolução in vitro pela técnica de DNA Shuffling.
(Universidade Federal de São Carlos, 2004-11-26)
Plants seem to have developed, over a long period of time, defence mechanisms against fungi and insects. One of them is the use of protease inhibitor proteins. Cystatins are proteins that inhibit specifically cysteine ...
Expressão heteróloga e localização subcelular de seis proteínas possivelmente envolvidas com a Síndrome de Down.
(Universidade Federal de São Carlos, 2004-12-07)
Down syndrome (DS) is the most common congenital disease occurring in
approximately 1 out of 700 live births. In addition to the full HC21 trisomy, rare
individuals with clinically recognized DS have only a partial trisomy, ...
Produção recombinante e estudos funcionais de três novas cistatinas da cana-de-açúcar e sua utilização em estudos de inibição da adesão, proliferação, migração e invasão celular
(Universidade Federal de São Carlos, 2008-02-29)
ABSTRACT
Tumor metastasis is usually a major cause of death among cancer patients.
Degradation and invasion of the extracellular matrix and basement membrane, key
steps in the metastatic process, rely on the activity of ...