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Análise de genes e proteínas envolvidos no estado redox de reticulócitos e eritrócitos de pacientes beta talassêmicos ou com anemia falciforme
(Universidade Federal de São Carlos, 2018-06-27)
Although not the primary etiology of diseases such as beta-thalassemia and sickle cell anemia, oxidative damage plays a crucial role in the aggravation of these diseases, contributing to the hemolysis and the short survival ...
SNPs no gene da HSC70 e suas implicações na carcinicultura e conservação dos estoques de camarão-da-amazônia (Macrobrachium amazonicum)
(Universidade Federal de São Carlos, 2013-06-14)
Macrobrachium amazonicum is an endemic species in South America, which has been exploited by artisanal fisheries in northern and northeastern Brazil. The overexploitation of this species has led to the decline of its natural ...
Estudo do efeito da Alternagina-C, uma desintegrina do veneno de Bothrops alternatus,sobre a adesão de células normais e tumorais. Avaliação do seu potencial como agente anti-metastático.
(Universidade Federal de São Carlos, 2004-11-26)
The α2β1 integrin is a major collagen receptor that plays an essential role in the
normal and tumor cells adhesion to the extracellular matrix, as well as in the
metastasis. Antagonists of integrins have been ...
Degradação de matéria orgânica terrestre por microrganismos do rio Amazonas – Metagenômica e genômica populacional
(Universidade Federal de São Carlos, 2018-12-14)
Microbes from Amazon river basin represent an unexplored biodiversity, with a huge metabolic potential. This ecosystem receives large amounts of terrestrial organic matter (OM), which promotes heterotrophic microbial growth. ...
Biologia molecular aplicada à identificação de alvos para o controle do bicudo da cana-de-açucar, Sphenophorus levis
(Universidade Federal de São Carlos, 2012-02-29)
The sugarcane weevil, Sphenophorus levis, is an insect that feeds on the rhizome of sugarcane in its larval stage, boring channels that cause damage and death to the plant. Conventional methods of insect control have not ...
Efeitos das desintegrinas Alternagina-C e DisBa-01 de Bothrops alternatus em fibroblastos, células endoteliais e tumorais
(Universidade Federal de São Carlos, 2009-11-17)
Disintegrins are small cysteine-rich proteins with an RGD motif isolated from viperidae snake venoms. DisBa-01, a recombinant RGD-disintegrin from Bothrops alternatus snake venom, inhibits melanoma cell metastasis and also ...
Distribuição da variação genética nos canídeos Cerdocyon thous e Chrysocyon brachyurus de paisagens antropizadas da região centro-oeste e sudeste do Brasil
(Universidade Federal de São Carlos, 2017-08-24)
The Crab-eating fox (Cerdocyon thous) and the Maned Wolf (Chrysocyon brachyurus) are a fundamental part from the habitats where they occur, due to the ecosystemic functions they play, as seed dispersers and controlling the ...
Genética populacional de felinos e as ameaças para Puma concolor: estruturação populacional recente e atropelamentos
(Universidade Federal de São Carlos, 2018-06-25)
Species around the world are increasingly exposed to new threats due to human activities. The main threat is the landscape modification by human activities, resulting in demographic and genetic pattern changes of species ...
Expressão gênica associada ao conteúdo de minerais no músculo Longissimus thoracis e seus processos regulatórios em bovinos Nelore (Bos indicus)
(Universidade Federal de São Carlos, 2019-09-06)
The mineral concentration of the bovine muscle does not only depend on the balance between the ingestion and excretion of minerals, but also the environment, breed and genetic factors. In addition, mineral content can ...
Prospecção de regiões pleiotrópicas para características complexas relevantes ao melhoramento bovino a partir de GWAS bi-característica
(Universidade Federal de São Carlos, 2019-05-31)
The demand for sustainable beef production systems drives the development of new tools that aim to reduce the production costs and to avoid losses in meat quality. The objective of this study was to identify possible ...