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Mecanismos de regulação da via de sinalização Wnt pela E3 ubiquitina ligase SCF(Fbxo7)
(Universidade Federal de São Carlos, 2019-02-22)
SCF complexes are composed by Skp1, Cullin1, Rbx1 and an F-box protein (FBP), which are responsible to give specificity to the complexes, as they interact with substrates, allowing ligation of an ubiquitin molecule to the ...
Clonagem e Expressão Heteróloga de Proteínas Estruturais (C, prM, E) de Zika Virus (ZIKV)
(Universidade Federal de São Carlos, 2018-08-31)
Viruses are organisms which depend on the host cellular machinery to replicate,
and are relevant to human, livestock and plant health. The modern threat of emerging
pandemics is pressing and, in this scenario, Zika Virus ...
Análise e contribuições para o ensino de biologia molecular em um município do interior paulista
(Universidade Federal de São Carlos, 2018-10-01)
Currently the number of works that seek to understand the difficulties involved in the teaching and learning process in Biology field, more specifically in the Molecular Biology subfield, has been grown exponentially. Such ...
Efeito do knockout da Mitofusina 1 sobre a fertilidade de oócitos murinos
(Universidade Federal de São Carlos, 2018-08-31)
Fertility is directly related to oocyte developmental competence. In this context, oocyte mitochondria play a crucial role and have become an important target in assisted reproduction therapies. However, the molecular ...
Papel do domínio desintegrina da ADAM9 humana na modulação da migração e invasão de células tumorais
(Universidade Federal de São Carlos, 2011-02-25)
Cancer metastasis is the major cause of death, consequently studies to understand the molecular mechanisms involved in this process are essential to the knowledge of this disease. Cell migration and invasion are part of ...
Análises Bioinformáticas de Proteínas de Resistência do Tipo Nucleotide Binding Site-Leucine Rich Repeat (NBS-LRR) de Café
(Universidade Federal de São Carlos, 2019-02-15)
The molecular factors involved in the coffee’s resistance to rust and other diseases have not been completely known, but related projects have been developed since the last century. One of the main problems that make ...
Obtenção de uma desintegrina recombinante de Agkistrodon contortrix laticinctus e estudo dos efeitos de desintegrinas na expressão do fator de crescimento de endotélio vascular.
(Universidade Federal de São Carlos, 2005-02-17)
Disintegrins are snake venom proteins used in the study of integrin-mediated cellular
adhesion through integrins. Recombinant disintegrin production may notable supply faster,
larger and most homogeneous protein samples ...
Produção heteróloga de inibidores de pectina metil esterase (PMEI), para ensaios de inibição com PME e Invertase, enzimas intestinais do Sphenophorus levis
(Universidade Federal de São Carlos, 2018-02-20)
The pectin is a fundamental part of the cell wall from plants and it is composed mainly by 4 polysaccharides. The polysaccharide most abundant is the homogalacturonan (HG) representing up to 65% from pectin, and it is a ...
Isolamento e caracterização de cepas termotolerantes de Saccharomyces cerevisiae e análise da expressão de genes possivelmente envolvidos com a termotolerância
(Universidade Federal de São Carlos, 2018-03-28)
Brazil is the world’s second largest producer of ethanol, which is produced, in our country, from the fermentation of sugarcane sucrose by Saccharomyces cerevisiae yeast. Despite having a high capacity for ethanol production, ...
Comparação da capacidade de formulações medicamentosas de diferentes quimioterápicos em induzir morte celular em células da linhagem MB49 de tumor de bexiga murino
(Universidade Federal de São Carlos, 2018-03-29)
Despite recent advances in cancer prevention and treatment, bladder urothelial carcinoma continues to be one of the most common types of malignant neoplasms in the world, with a 20% mortality rate. The cells and molecules ...