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Eficácia da instilação de células da linhagem MB49 e gel polimérico termorreversível na imunização contra o carcinoma urotelial de bexiga
(Universidade Federal de São Carlos, 2020-09-24)
Among the various types of malignant neoplasms, those originating in the bladder can be considered highly impactful due to their prevalence and high recurrence rates, demonstrating the importance of studies involving new ...
Investigação dos mecanismos envolvidos na herança mitocondrial: o papel da dinâmica mitocondrial
(Universidade Federal de São Carlos, 2020-10-08)
Diseases caused by mutations in mitochondrial DNA (mtDNA) are the most common genetic diseases in humans. Despite this, there is no effective treatment for these diseases and the mechanisms of inheritance are not fully ...
Viabilidade de grãos de pólen de espécies de Paspalum após a criopreservação visando seu uso em programas de melhoramento genético
(Universidade Federal de São Carlos, 2020-02-28)
Paspalum is a genus of the Poaceae family, native to America, of which many species have forage potential. The high natural genetic diversity observed in the genus can be used to obtain and launch new cultivars. For ...
Estudo dos efeitos antiangiogênicos da desintegrina-símile Alternagina-C (ALT-C) em células endoteliais (HUVEC), tendo como alvo a integrina α2β1
(Universidade Federal de São Carlos, 2020-03-04)
Angiogenesis is a crucial process in tumor progression, and it is mainly regulated by the vascular endothelial growth factor (VEGF) and its receptor, VEGFR2. Studies have shown that VEGF/VEGFR2 axis signaling is directly ...
Estudos cromossômicos clássicos e moleculares no complexo de espécies Astyanax scabripinnis (Characiformes, Characidae)
(Universidade Federal de São Carlos, 2020-08-26)
Astyanax is a fish genus of Characiformes and currently is classified as incertae sedis. Astyanax scabripinnis, one of these species, is recognized as a species complex, which is composed of 33 species. This study propose ...
Sítios cromossômicos instáveis e diversificação cariotípica em Loricariidae: análise citogenética e molecular
(Universidade Federal de São Carlos, 2022-07-15)
Loricariidae includes species vulgarly known as armored catfishes. Cytogenetic data revealed wide chromosomal diversity in this family, resulted from both diploid number (2n) variation, because of centric fusion events, ...
Caracterização de pontos de quebras de DNA e rearranjos cromossômicos no gênero Harttia (Siluriformes: Loricariidae)
(Universidade Federal de São Carlos, 2022-04-04)
Harttia genus comprises a fish group widely distributed in hydrographic basins of South
America. In the cytogenetic point of view, present large karyotypic variation, including
an extensive variation in position of ...
Papel das integrinas αvβ3 e α5β1 na migração de células de tumor de mama triplo negativo e células endoteliais em hipóxia
(Universidade Federal de São Carlos, 2022-04-14)
Breast tumors show high incidence and mortality for female oncologic cases in 2020. Tumor microenvironment presents several elements, such as extracellular matrix (ECM). ECM proteins bind to cells through receptors such ...
Genômica populacional do Mico-Leão-Preto (Leontopithecus chrysopygus, Mikan 1823): uma espécie ameaçada de extinção
(Universidade Federal de São Carlos, 2021-12-01)
The species Leontopithecus chrysopygus, endemic to the Atlantic Forest of the state of São Paulo, is considered endangered by the IUCN and IBAMA. It is estimated that currently the free-living population of this species ...
Isolamento e caracterização de vB_XciM_LucasX, um novo bacteriófago lítico de Xanthomonas citri e Xanthomonas fuscans
(Universidade Federal de São Carlos, 2022-09-16)
Citrus canker, which is caused by the bacteria Xanthomonas citri and Xanthomonas fuscans, is one of the main diseases that affect the citrus industry in Brazil. Disease control methods are available, but new methods are ...