Browsing Teses e dissertações by Advisor "c9d783c2-174c-4a51-9643-0e44f6fc9ac9"
Now showing items 1-13 of 13
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Arilsulfonilação tri componente de diidrofurano e ésteres vinílicos via catálise dual níquel/fotorredox
(Universidade Federal de São Carlos, UFSCar, Programa de Pós-Graduação em Química - PPGQ, Câmpus São Carlos, 29/03/2022)The pursuit of synthetic protocols aligned to sustainability goals, increasingly necessary in the global context in which we operate, caused a great effort by synthetic chemists to develop photocatalytic methodologies ... -
Multicomponent reactions in the discovery of organocatalysts and the diversification of organocatalytic approaches
(Universidade Federal de São Carlos, UFSCar, Programa de Pós-Graduação em Química - PPGQ, Câmpus São Carlos, 19/06/2015)This thesis reports the development of multicomponent approaches directed to specific objectives: a) the discovery of new and efficient peptide-based catalyst for asymmetric transformations and b) the synthesis of ... -
Asymmetric induction on isocyanide-based transformations: development of stereoselective Ugi-type reactions
(Universidade Federal de São Carlos, UFSCar, Programa de Pós-Graduação em Química - PPGQ, Câmpus São Carlos, 26/05/2023)The design of new synthetic transformations that rapidly allow construction of structurally complex molecules from simple starting materials under both concepts of diversity and function-oriented syntheses is extremely ... -
Multicomponent approach to silica-grafted peptide catalysts : A 3 D continuous-flow organocatalytic system with on-line monitoring of conversion and stereo-selectivity
(Universidade Federal de São Carlos, UFSCar, Programa de Pós-Graduação em Química - PPGQ, Câmpus São Carlos, 28/11/2014)The derivatization of organocatalysts with functional appendages suitable to anchor onto solid supports is usually achieved by stepwise syntheses. As an alternative to such a strategy, this work describes a one-pot approach ... -
Tris(trimethylsilyl)silane and visible-light irradiation : a new metal- and additive-free photochemical process for the synthesis of indoles and oxindoles
(Universidade Federal de São Carlos, UFSCar, Programa de Pós-Graduação em Química - PPGQ, Câmpus São Carlos, 29/07/2016)A combined tris(trimethylsilyl)silane and visible-light-promoted intramolecular reductive cyclization protocol for the synthesis of indoles and oxindoles has been developed (Scheme 1).1 This straightforward and efficient ... -
Nanoestructured catalysts for organic reactions: design, synthesis and applications
(Universidade Federal de São Carlos, UFSCar, Programa de Pós-Graduação em Química - PPGQ, Câmpus São Carlos, 29/07/2016)The development of more efficient and selective catalysts actively contributes for the design of safer, cleaner and less energy-demanding processes, and, therefore, catalysis is one of the cornerstones of green chemistry. ... -
Conjugate additions and organocatalytic sequential reactions - new approaches to old reactions
(Universidade Federal de São Carlos, UFSCar, Programa de Pós-Graduação em Química - PPGQ, Câmpus São Carlos, 01/04/2016)This thesis consists in a collection of projects wherein the focus is the application of organocatalysts to accelerate the reactions, its primary function, as to induce asymmetry to the synthetic targets, within a ... -
Síntese de precursores de heterociclos e sistemas cíclicos nitrogenados
(Universidade Federal de São Carlos, UFSCar, Programa de Pós-Graduação em Química - PPGQ, Câmpus São Carlos, 23/03/2018)β-halovinyl ketones are valuable and versatile synthetic intermediates for the synthesis of precious bioactive molecules. Majority of the already described methodologies for the synthesis of these versatile building blocks ... -
Flow Chemistry: From assembly to the application
(Universidade Federal de São Carlos, UFSCar, Programa de Pós-Graduação em Química - PPGQ, Câmpus São Carlos, 17/12/2018)Over the centuries, chemical reactions have been carried out in the same way in standardized glassware. On the other hand, continuous flow reactions are gaining interest regularly and demand for the related hardware toolkit ... -
Photoredox-mediated aminoalkylation and carbamoylation of azomethine imines
(Universidade Federal de São Carlos, UFSCar, Programa de Pós-Graduação em Química - PPGQ, Câmpus São Carlos, 25/08/2021)Over the past decade, the organic synthetic community has witnessed the emergence of a new and complementary approach to the conventional radical chemistry. Photochemistry has proven to be a powerful and more sustainable ... -
Síntese de derivados de asparaginas não-naturais N4-substituídas e modificação de peptídeos: adição fotoredox de radicais carbamoil à dehidroalanina
(Universidade Federal de São Carlos, UFSCar, Programa de Pós-Graduação em Química - PPGQ, Câmpus São Carlos, 27/08/2021)The development of sustainable methodologies for the synthesis of byologic relevant molecules is of great importance for both, academia (especially in organic synthesis and medicinal chemistry) and pharmaceutical industry. ... -
Multicomponent combinatorial synthesis of proplyl peptide-lipopeptoid hybrid catalyst: application in the asymmetric Michael addition under aqueous environment
(Universidade Federal de São Carlos, UFSCar, Programa de Pós-Graduação em Química - PPGQ, Câmpus São Carlos, 29/11/2018)This study describes the synthesis of a new library of prolyl peptides-lipopeptoid hybrids catalysts through a multicomponent combinatorial approach. For the design of this catalyst library, we took into consideration the ... -
Organocatálise assimétrica e sistemas vinílogos: adição de 1,3-oxazolina-2-tionas a aldeídos a,b-insaturados
(Universidade Federal de São Carlos, UFSCar, Programa de Pós-Graduação em Química - PPGQ, Câmpus São Carlos, 16/03/2017)The use of organic molecules in stereoselective transformations has emerged as a powerful tool for the efficient construction of chiral skeletons and complementing existing methods. Currently, a great variety of reactions ...