Buscar
Itens para a visualização no momento 41-50 of 75
Estudos teóricos e experimentais de complexos de cobre: propriedades espectroscópicas e atividade biológica
(Universidade Federal de São Carlos, 2020-07-28)
Cancer is the second leading cause of death in the world. The scientific community is mobilizing to study new compounds with cytotoxic potential and that can be used as molecular probes. However It is important to highlight ...
Calibração multivias em Laser-Induced Breakdown Spectroscopy (LIBS) para determinação de Ca, K e Mg em amostras de suplemento mineral para humanos
(Universidade Federal de São Carlos, 2021-03-25)
This work intends to present a new approach for modeling LIBS data resolved in time using multiway algorithms, aiming to achieve the advantage of second order. The algorithms evaluated in this study were: Multivariate Curve ...
Planejamento experimental aplicado aos estudos de degradação forçada do fármaco Ticagrelor
(Universidade Federal de São Carlos, 2020-08-31)
Stability indicating tests are an essential part during pharmaceutical drug production, besides being a mandatory step for the regulation and approval from the regulatory agencies. Forced degradation consist of an exposure ...
Estudo espectroscópico por FTIR da conversão de etanol em catalisadores de Au suportados
(Universidade Federal de São Carlos, 2020-07-25)
In this work, an FTIR spectroscopic study of gold catalysts supported on monoclinic zirconia (with Au content of 2,5% w/w), was carried out in order to elucidate the surface nature of this catalyst in the dehydrogenation ...
Avaliação in vitro da ação fotodinâmica antimicrobiana e antitumoral do complexo cis-[Ru(phen)2(pPDIp)]2+
(Universidade Federal de São Carlos, 2021-02-19)
Photodynamic therapy (PDT) activates a photosensitizer by visible or infrared light to generate cytotoxic oxygen species that lead to cell death. PDT is generally used in applications in superficial lesions and can be used ...
Imagens espectrais do processo de agregação da insulina por complexos metálicos luminescentes
(Universidade Federal de São Carlos, 2021-03-01)
Insulin is a protein hormone synthesized by β cells in the pancreas, which regulates the level of glucose in the blood. This protein was the first biopharmaceutical produced on an industrial scale for the treatment of ...
Síntese de complexos de Mg(II), atividade antioxidante e citotóxica
(Universidade Federal de São Carlos, 2021-03-09)
The objective of this work was to develop metal complexes containing natural products that have antioxidant activity to be applied in the cosmetics sector. For that, 3 [Mg(phen)2PN]+ metal complexes were synthesized and ...
Evaluation of the biological activity of the disintegrin-like and cysteine-rich domains of Bothropasin, a metalloproteinase from Bothrops jararaca
(Universidade Federal de São Carlos, 2021-05-17)
Bothropasin is a 48kDa hemorrhagic class III Snake Venom Metalloproteinase (SVMP). As a multi-domain protein, it contains catalytic metalloproteinase (M), disintegrin-like (D), and cysteine rich domains (C). Integrins ...
Determinação de Si e Y em amostras agronômicas por espectrometria de emissão óptica com plasma induzido por micro-ondas
(Universidade Federal de São Carlos, 2021-05-20)
Different demands for analytical responses are presented in agricultural research. In this approach, this dissertation, divided into two chapters, seeks to offer analytical alternatives for plant breeding and fish nutrition ...
Eletrodo de pasta de carbono modificado com solvente eutético profundo hidrofóbico e sua aplicação voltamétrica
(Universidade Federal de São Carlos, 2021-03-01)
In this work, the use of hydrophobic deep eutectic solvent was proposed for the modification of carbon paste electrodes. Different HDES were prepared using fatty acids: octanoic, decanoic, and dodecanoic acids, and ...