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Identificação assistida por docking molecular de potenciais alvos em Plasmodium falciparum para derivados de indol-3-glioxiltirosina com atividade antimalárica in vitro
(Universidade Federal de São Carlos, 2020-07-28)
Malaria, although it is no longer considered a neglected disease, remains a public health problem. In 2018 alone, the World Health Organization estimated 228 million new cases and 405,000 deaths worldwide. Currently, ...
Estudos teóricos e experimentais de complexos de cobre: propriedades espectroscópicas e atividade biológica
(Universidade Federal de São Carlos, 2020-07-28)
Cancer is the second leading cause of death in the world. The scientific community is mobilizing to study new compounds with cytotoxic potential and that can be used as molecular probes. However It is important to highlight ...
Estudo de distintos processos oxidativos avançados eletroquímicos (e-POA) e teste de um reator solar em escala semi-piloto
(Universidade Federal de São Carlos, 2021-02-12)
In this work, two different advanced oxidation processes (AOP) were investigated: i) electrochemical processes (electro FeredFenton and photoelectro Fered-Fenton with BDD and DSA® electrodes under UVA/UVC irradiation (9 ...
Sachês compósitos biodegradáveis à base de amido visando o acondicionamento de nutrientes para aplicação como fertilizantes
(Universidade Federal de São Carlos, 2020-07-31)
The Brazilian agrarian system is responsible for a large part of the national GDP, even though agricultural production is dependent on foreign trade. In addition, many producers prioritize the use of NPK-type fertilizers ...
Determinação de impurezas inorgânicas em medicamentos: avaliação de preparo de amostra e medidas espectroanalíticas
(Universidade Federal de São Carlos, 2021-06-16)
Green sample preparation procedures were developed in this dissertation for determination of elemental impurities in drugs and dietary supplements by argon-based plasma spectroanalytical methods according to Chapters 232, ...
Obtenção de sulfetos metálicos (M= Ni, Mo) pelo método solvotermal assistido por micro-ondas aplicados na reação de desprendimento de hidrogênio
(Universidade Federal de São Carlos, 2020-03-27)
In general, transition metal sulfides show good activity in the Hydrogen Evolution Reaction (HER). Some of these metals, such as Mo and Ni, arouse interest in the area of electrocatalysis, since they are more abundant and ...
Síntese de miméticos da urease de Canavalia ensiformis e avaliação mecanística da decomposição da ureia
(Universidade Federal de São Carlos, 2020-02-20)
Urease is a metalloenzyme found in many different organisms, which is also associated to virulence factors, such as pielonefritis. Hence, the study of urease inhibitors is necessary to control its activity. For a better ...
Síntese de complexos de Mg(II), atividade antioxidante e citotóxica
(Universidade Federal de São Carlos, 2021-03-09)
The objective of this work was to develop metal complexes containing natural products that have antioxidant activity to be applied in the cosmetics sector. For that, 3 [Mg(phen)2PN]+ metal complexes were synthesized and ...
Desenvolvimento de eletrodo modificado com o solvente eutético profundo cloreto de colina/glicerol para a determinação simultânea de paracetamol e diclofenaco
(Universidade Federal de São Carlos, 2021-04-22)
In this master’s dissertation has investigated the use of deep eutectic solvents (DES) for the development of electrochemical sensors. DES was immobilized on the surface of a glassy carbon electrode (GCE) within carbon ...
UVC-based advanced oxidation processes for water treatment: laboratory and pilot plant scale studies
(Universidade Federal de São Carlos, 2020-09-21)
The challenge of providing good-quality water free from contaminants of emerging concern (including organic microcontaminants; OMCs) and pathogens is one of the main hot topics worldwide. Thus, the efficiency of different ...