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A aprendizagem de catálise enzimática por meio de casos: proposta para o ensino de química
(Universidade Federal de São Carlos, 2018-11-09)
The fundamental aim of provoking innovative forms of knowledge construction in Chemistry during basic education requires the instrumentalization of strategies that can show re-significances of pedagogical practices and ...
Synthesis of N-heterocycles and building blocks using multicomponent, photochemical and electrochemical approaches
(Universidade Federal de São Carlos, 2020-02-17)
Multicomponent reactions and protocols mediated by light and electrochemistry are powerful tools for modern organic synthesis. Moreover, they obey several principles of green chemistry such as atom economy, catalysis, waste ...
Estudo de complexos metálicos de RuII, NiII, PdII e PtII com ligantes aciltioureias: atividade citotóxica e interação com biomoléculas
(Universidade Federal de São Carlos, 2019-12-20)
In this work, two series of phosphine complexes containing acylthiourea ligands were synthesized, characterizatied and evaluatied of the cytotoxic activities. The first series of compounds was composed of complexes with ...
Estudo de inibidores naturais e sintéticos de cisteíno proteases
(Universidade Federal de São Carlos, 2018-11-30)
This work describes in its first part the chemical study of the fungus Fusarium proliferatum looking for inhibitors of cysteine proteases, with two distinct approaches: i) The search for papain inhibitors, to understand ...
Papaína imobilizada em partículas magnéticas: novos modelos de triagem de ligantes
(Universidade Federal de São Carlos, 2019-03-29)
Cathepsins, human lysosomal enzymes, are associated with the development of various diseases, and cruzaine is an important enzyme in the development of the protozoan Trypanosoma cruzi, causes Chagas' disease. Cysteine ...
Estudo do método de obtenção de membranas assimétricas de polietersulfona contendo complexos de polieletrólitos
(Universidade Federal de São Carlos, 2020-04-03)
Compared with traditional separation methods, polymeric membranes have low operation cost, fast separation rate and versatility. One interesting way of changing membrane properties is mixing additives into the polymeric ...
Síntese e caracterização de vanadatos de prata e formação de nanopartículas de prata por eletro-Irradiação
(Universidade Federal de São Carlos, 2018-02-19)
Due to its physico-chemical, bactericidal and photocatalytic properties, Silver vanadium oxides (SVOs) have attracted increasing attention due to their excellent physicochemical properties and diverse applications. The aim ...
Desenvolvimento de um método para quantificação simultânea de sulfametoxazol e trimetoprima em ovos de galinha utilizando a cromatografia liquida de alta eficiência bidimensional
(Universidade Federal de São Carlos, 2007-04-13)
This work reports the investigation of a series of bovine serum albumin (BSA) restricted access media columns (RAM) for on-line egg samples deproteinization. High exclusion percentage of egg s proteins were obtained with ...
Síntese de porfirinas contendo grupos do tipo uracil fundidos nas posições β-pirrólicas
(Universidade Federal de São Carlos, 2014-07-28)
In this work the synthesis of new porphyrin derivatives were proposed. The preparations of new compounds containing uracil groups at β-pirrolic position were studied based on their interest in organics synthesis. We ...
Avaliação da atividade bactericida e antineoplásica de novos complexos de Ag(I) contendo semicarbazonas e trifenilfosfina como ligantes
(Universidade Federal de São Carlos, 2019-09-27)
Title: EVALUATION OF BACTERIAL ACTIVITY AND ANTINEOPLASTIC OF NEW Ag(I) COMPLEXES CONTAINING SEMICARBAZONES AND TRIPHENYLPHOSPHINES AS LIGANDS. The present work aimed to evaluate the influence of ligands triphenylphosphine ...