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Mostrando ítems 321-330 de 350
Fosfoenolpiruvato carboxiquinase imobilizada: novos modelos de triagem de ligantes
(Universidade Federal de São Carlos, 2019-08-30)
Phosphoenolpyruvate carboxykinase (PEPCK) is a ubiquitous enzyme found in all known groups of organisms, acting in the reversible conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) and CO2, in the presence of ...
Complexos semi-sanduíche de RuII/areno e produtos naturais: uma promissora combinação para novos metalofármacos
(Universidade Federal de São Carlos, 2020-10-15)
This thesis presents the synthesis, characterization and evaluation of antitumor activity of nineteen neutral and monocatonic organometallic complexes containing ligands derived from natural products. The complexes were ...
Estudos bioquímicos e cinéticos de acetilcolinesterases de formigas cortadeiras (Atta sexdens)
(Universidade Federal de São Carlos, 2017-09-29)
Acetylcholinesterase (AChE) (EC 3.1.1.7) is the enzyme responsible for catalyzing the hydrolysis of the neurotransmitter acetylcholine leading to the release of acetate and choline. In insects, acetylcholine is one of the ...
Abordagem investigativa como fator de motivação em três cursos da área de Química de uma instituição pública do Estado de São Paulo
(Universidade Federal de São Carlos, 2020-08-07)
Laboratory classes have great potential to motivate students in science courses, whether to learn new knowledge or to demonstrate what they have already learnt. There are some ways of working in the laboratory and two draw ...
Picramnia glazioviana and Picramnia bahiensis as source for new natural products. Insecticidal and fungicidal evaluations and High-Resolution Bioassay/HPLC-HRMS-SPE/NMR studies
(Universidade Federal de São Carlos, 2018-04-27)
Leaf-cutting ants of the genus Atta and Acromyrmex are considered the most important pests in agriculture, pastures, and reforestation programs due to the defoliation caused by the uncontrolled herbivory that the plants ...
Supramolecular synthesis and characterization of new multicomponent forms of fluconazole
(Universidade Federal de São Carlos, 2020-06-30)
Active Pharmaceutical Ingredient (API) is the therapeutic constituent that defines the pharmacological properties and performance of the drug. Their qualities vary due to their respective physicochemical and pharmacological ...
Identificação assistida por docking molecular de potenciais alvos em Plasmodium falciparum para derivados de indol-3-glioxiltirosina com atividade antimalárica in vitro
(Universidade Federal de São Carlos, 2020-07-28)
Malaria, although it is no longer considered a neglected disease, remains a public health problem. In 2018 alone, the World Health Organization estimated 228 million new cases and 405,000 deaths worldwide. Currently, ...
Electrochemistry and STM-assisted Molecular electronics study of bimetallic hexaphyrins
(Universidade Federal de São Carlos, 2019-09-23)
ELECTROCHEMISTRY AND STM-ASSISTED MOLECULAR ELECTRONICS STUDY OF BIMETALLIC HEXAPHYRINS. The electron transport in porphyrinoids are related to several bioprocesses in Nature, from conversion from solar energy to chemical ...
Obtenção de derivados de compostos isolados de Zingiber officinale por biotransformação e semi-síntese e avaliação frente à cisteinil-proteases
(Universidade Federal de São Carlos, 2016-07-01)
Several aromatic polyketide derivatives from Ginger (Zingiber officinale), like zingerone,
6-gingerol and 6-shogaol were obtained by biocatalytic reactions and semi-synthesis and
both their antifungal and cysteine-proteinase ...
Avaliação do comportamento de BTEX e seus metabólitos de biodegradação em solos: estudos de remedição em microcosmos
(Universidade Federal de São Carlos, 2015-08-28)
The monoaromatic hydrocarbons composed by benzene, toluene, ethylbenzene and xylenes isomers (BTEX), are commonly found near local oil refineries, filling stations, or around pipelines, as a result ofleaks and/or spills. ...